Objective(s) Previous studies have demonstrated that pretreatment with alpha-tocotrienol (a-TCT) can reduce ischemic damage in mice following middle cerebral artery (MCA) occlusion. It is also reported to decrease stroke- dependent brain tissue damage in 12-Lox-deficient mice and spontaneously hypertensive rats. In the present study, the neuroprotective effects of a-TCT and rosiglitazone (RGZ)...

Introduction: Black pepper (Piper nigrum L.) is one of the medicinal plants being used to prevent and manage stroke in Persian Medicine. Current findings support its anti-inflammatory, radical scavenging and neuroprotective characteristics. In this study, we aimed to evaluate role of black pepper on functional and histopathological outcomes of stroke in an animal model of MCAO. Materials and Me...

We have examined the usefulness of transoesophageal echocardiography (TOE) and automated endocardium detection for on-line calculation of left ventricular stroke volume. In 12 of 15 patients undergoing abdominal surgery, stroke volume was derived continuously from the multiple discs (MD) and area-length (AL) methods and compared with stroke volume calculated by thermodilution. In 10 patients (8...

In chronic obstructive pulmonary disease (COPD) patients, stroke volume response to exercise is impaired. The aim of the present study was to investigate whether 3 months of sildenafil treatment improves stroke volume and, if so, whether this improvement is related to the pulmonary artery pressure and translated into an improved exercise capacity. A total of 15 stable COPD patients (Global Init...

background: intracerebral  hemorrhage (ich) is the  most fatal subtype  of stroke.  despite  limited effective therapy, there  is no  accepted clinical grading  scale to  predict  in- hospital  mortality,  especially  in developing  nations.  the purpose  of this study was to assess the  predictors  of in- hospital mortality among a sample of iranian patients  with spontaneous ich for use at th...

To characterize the hemodynamic factors that regulate stroke volume during upright exercise in normal man, 24 asymptomatic male volunteers were evaluated by simultaneous right heart catheterization, radionuclide angiography, and expired gas analysis during staged upright bicycle exercise to exhaustion. From rest to peak exercise, oxygen consumption increased from 0.33 to 2.55 liters/min (7.7-fo...

The linear dimensions of the ventricle of an in situ perfused trout heart were measured with an ultrasound scanner. Using a pyramidal model, linear dimensions taken from real-time, two-dimensional, echotomographic images of the ventricle were used to calculate ventricular end-diastolic and end-systolic volumes and, by the difference between them, stroke volumes for various filling and output pr...

The feasibility of using continuous on-line recording of intraventricular electrical impedance to measure ventricular stroke volume was assessed in 12 patients at cardiac catheterization with a multielectrode impedance catheter and a 1.3 kHz measuring current of 4 microA. Stroke volumes determined by electrical impedance were compared with stroke volumes determined by the thermodilution techniq...