Biological activity of a synthetic peptide with inhibin-like activity under in vitro and in vivo conditions was compared with three highly potent synthetic lutropin-releasing hormone antagonists. Unlike the synthetic lutropin-releasing hormone antagonists, which effectively inhibited both lutropin and follitropin secretion from the pituitary, the inhibin-like peptide showed a preferential effec...

Aims and Objectives: This study aimed to assess compare follicle-stimulating hormone (FSH), luteinizing (LH), prolactin, thyroid-stimulating (TSH) levels in normal fertile females, patients with primary infertility, early pregnancy loss (EPL). Methods: Patients were divided into three groups of 25 each. Group I consisted II EPL, C females acted as the control group. Hormone different compared s...

· Growth hormone (GH), which is essential for growth · Thyroid stimulating hormone (TSH), which regulates thyroid function · Prolactin (PRL), which is essential for lactation · Follicle stimulating hormone (FSH) and Luteinizing hormone (LH), which are essential for ovulation in female animals and sperm production in male animals · Adrenocorticotroph hormone (ACTH), which stimulates the adrenal ...

Sertoli cells under the influence of Follicle Stimulating Hormone are known to provide a microenvironment for the growth and differentiation of germ cells. Follicle Stimulating Hormone regulates proliferation of Sertoli cells only during the early neonatal period and during adult period it regulates functional parameters like Transferrin, Androgen binding protein and other factors needed for ge...

OBJECTIVE: To compare the diagnostic accuracy of Anti-Mullerian hormone with follicle stimulating hormone for ovarian reserve assessment in infertile women by Receiver Operator Characteristic curve analysis. STUDY DESIGN: A Cross Sectional study. PLACE AND DURATION OF STUDY: At Institute of Basic Medical Sciences, University of Health Sciences in collaboration with nd th Gynecology and Obstetri...

We investigated thyroid function in 119 survivors of treatment for brain tumours not involving the hypothalamo-pituitary region. Cranial irradiation did not effect thyroid function but 11 of 47 children (23%) who had spinal irradiation had raised concentrations of thyroid stimulating hormone. Chemotherapy further increased the incidence of thyroid dysfunction: two of four patients who had crani...

Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...

Graves’ disease is an autoimmune syndrome where thyroid stimulating antibodies bind to and activate the thyrotropin receptor on thyroid cells resulting in hyperthyroidism (Weetman, 2000; Jonklaas, 2011). Specifically, the production of thyroid-stimulating immunoglobulin (TSI) and thyroid-stimulating hormone-binding inhibitory immunoglobulin (TBII) act on the thyroid stimulating hormone receptor...

In a screening programme for neonatal hypothyroidism an otherwise healthy female infant was found to have a high concentration of thyroid stimulating hormone in a filter paper blood spot and in serum. A high concentration was also found in the maternal serum. Mother and baby were both biochemically euthyroid with normal serum thyroxine concentrations. The apparently high concentration of thyroi...