BACKGROUND Decreasing the stiffness of locked plating constructs can promote natural fracture healing by controlled dynamization of the fracture. This biomechanical study compared the effect of 4 different stiffness reduction methods on interfragmentary motion by measuring axial motion and shear motion at the fracture site. METHODS Distal femur locking plates were applied to bridge a metadiap...

The present study evaluates how the soft first story irregularity condition should be defined: (a) as a significant reduction of the lateral shear stiffness of all resisting frames within a given story, as established in the seismic provisions of Mexican building codes or, (b) as a substantial reduction of the lateral shear stiffness of one or more resisting frames within a given story, as prop...

The recently proposed reduction method is applied to the Edwards-Anderson model on bond-diluted square lattices. In combination with a graph-theoretical matching algorithm, this allows us to calculate numerically exact ground states of large systems. Low-temperature domain-wall excitations are studied to determine the stiffness exponent y2. A value of y2=−0.281 3 is found, consistent with previ...

Passive stiffness characteristics of isolated cardiac myocytes, papillary muscles, and aortic strips from male Holtzman rats fed a copper-deficient diet for approximately 5 wk were compared with those of rats fed a copper-adequate diet to determine whether alterations in these characteristics might accompany the well-documented cardiac hypertrophy and high incidence of ventricular rupture chara...

Reversible changes in lung microstructure accompany lung inflammation, although alterations in tissue micromechanics and their impact on inflammation remain unknown. This study investigated changes in extracellular matrix (ECM) remodeling and tissue stiffness in a model of LPS-induced inflammation and examined the role of lipoxin analog 15-epi-lipoxin A4 (eLXA4) in the reduction of stiffness-de...

The ability to tune phagocytosis of particle-based therapeutics by macrophages can enhance their delivery to macrophages or reduce their phagocytic susceptibility for delivery to non-phagocytic cells. Since phagocytosis is affected by the physical and chemical properties of particles, it is crucial to identify any interplay between physical properties of particles in altering phagocytic interac...

In this paper, I explore the exponential Rosenbrock-type method of order two. It is an explicit method that solves stiff ODEs. The method linearizes the equation with each step, then uses a matrix exponential to solve the linearized equation exactly. Previous research has identified stability bounds and convergence results. In this paper, I explore the stiffness capabilities of this second orde...

in this article, vibration analysis of an euler-bernoulli beam resting on a pasternak-type foundation is studied. the governing equation is solved by using a spectral finite element model (sfem). the solution involves calculating wave and time responses of the beam. the fast fourier transform function is used for temporal discretization of the governing partial differential equation into a set ...

Among end-stage renal disease (ESRD) patients receiving hemodialysis, increased arterial stiffness is an independent cardiovascular risk predictor. Over the past few years, arterial stiffness attenuation has been increasingly recognized as a novel therapeutic target toward cardiovascular risk reduction in the dialysis population. Structural alterations related to the long-term arteriosclerotic ...