Salivary gland related bone defects or Stafne bone defects are asymptomatic bone cavities in the mandible caused by impingement by the salivary glandular tissue. All the three major salivary glands are in approximation with the mandible and depressions with each can produce radiolucent defects on the surface of the mandible. These bone defects or depressions are categorized as anterior lingual ...

Background & Objective: This study aimed to investigate the effect of decellularized allogeneic bone graft enriched by periosteal stem cells (PSCs) and growth factors on the bone repair process in a rabbit model, which could be used in many orthopedic procedures. Methods: In this experimental study, a critical size defect (CSD) (10 mm) was created in the ...

Background: Hypothyroidism is associated with dysfunction of the bone turnover with reduced osteoblastic bone formation and osteoclastic bone resorption. Mesenchymal stem cells (MSCs) secrete various factors and cytokines that may stimulate bone regeneration.  The aim of this study was to determine the effects of MSCs-conditioned medium (CM) in hypothyroidism male rats after inducing bone ...

background: bone tissue engineering requires materials that are biocompatible, mechanically suited for bone function, integrated with the host skeleton, and support osteoinduction of the implanted cells for new bone formation. the aim of this study was to compare the osteogenic potential of xenograft with hydroxyapatite/β- tricalcium phosphate (ha/β-tcp) scaffold. methods: new zealand rabbits (...

Objective- Current trends emphasize the acceleration of fracture healing on the ground that in doing so, the limitation of mobility and complications associated with recovery period are reduced. The present study aims to compare autogenic costal cartilage with Chitosan scaffold in canine humeral defect healing. Design- Experimental study Animal-15 adult male dogs Procedures-...

Objective- To evaluate the role of greater omentum incorporation of coral in healing of the long bone defect in dog model. Design- Experimental in-vivo study. Animals- Sixteen adult mongrel male dogs weighing 26.2±2.5 kg, free of evident infectious or parasitic illnesses were used in this study. Procedures- The operative procedure was undertaken under general anesthesia. Radial bone was expo...