Objective: The objective of the work was to develop and validate stability indicating HPTLC method for estimation Iguratimod. Methods: employed aluminium pre-covered silica gel 60 GF254 plates (10 cm × 10 with 250 μm layer thickness) as stationary phase while solvent system n-Hexane: Ethyl Acetate (5:5 v/v) densitometric scanning at 256 nm. Sample applied a band 8 mm width using Camag 100 μl sa...

Abstract Background A novel gradient, high-sensitive and specific stability-indicating reverse-phase HPLC method was developed validated for quantitative purpose of known, unknown degradant impurities profiling diltiazem hydrochloride tablets. The were separated on the Zorbax RX C8 column (150 mm × 4.6 mm, 5 μm) with mobile phase-A consisting a mixture 0.05 M sodium dihydrogen phosphate monohyd...

Fluvoxamine maleate is a selective serotonin reuptake inhibitor, which is used for the treatment of different types of depressive disorders. In the present study, a stability indicating HPLC method was developed and validated for the determination of fluvoxamine maleate. The chromatographic separation was carried out using a Nova-Pak CN column and a mixture of K2HPO4 50 mM (pH 7.0) and acetonit...