نتایج جستجو برای: ssc niche
تعداد نتایج: 26865 فیلتر نتایج به سال:
PURPOSE The optimal treatment of systemic sclerosis (SSc) is a challenge because the pathogenesis of SSc is unclear and it is an uncommon and clinically heterogeneous disease affecting multiple organ systems. The aim of the European League Against Rheumatism (EULAR) Scleroderma Trials and Research group (EUSTAR) was to develop evidence-based, consensus-derived recommendations for the treatment ...
Pulmonary disease is the leading cause of morbidity and mortality in patients with systemic sclerosis (SSc). Recent well-designed trials in SSc-associated interstitial lung disease (SSc-ILD) have provided important insights regarding outcome measures and trial design. Recent investigations into the pathogenesis of SSc-ILD have led to a renewed interest in assessing targeted therapies in SSc-ILD...
We explore the possibility that Z ′ couplings can be probed using decay modes which involve neutrinos once Standard Model backgrounds are directly determined by the data itself. For some models, sufficient statistics are available at either the SSC or LHC to render these modes useful for coupling determina-tions, provided the mass of the Z ′ is not much larger than 1 TeV, if we assume other new...
1Departments of Medicine and Dermatology, Division of Immunology and Rheumatology, Stanford University and Palo Alto VA Health Care System, CA, USA; 2Centre for Rheumatology, Royal Free Hospital, London, United Kingdom; 3Department of Rheumatology, University Hospital Zurich, Switzerland; 4Department of Medicine, Division of Rheumatology, University of California at Los Angeles, Los Angeles, US...
Résumé. Cet article se place dans le cadre du subspace clustering, dont la problématique est double : identifier simultanément les clusters et le sousespace spécifique dans lequel chacun est défini, et caractériser chaque cluster par un nombre minimal de dimensions, permettant ainsi une présentation des résultats compréhensible par un expert du domaine d’application. Les méthodes proposées jusq...
P.N. Appleton (IPAC), A.W. Blain (Caltech), C.M. Bradford (JPL), C.R. Bridge (SSC), R. Chary (SSC), E. Daddi (CEA Saclay), V. Desai (SSC), M. Harwit (Cornell), G. Helou (IPAC), P.F. Hopkins (UC Berkeley), M. Malkan (UCLA), J. Melbourne (Caltech), E.J. Murphy (SSC), P. Ogle (SSC), C. Papovich (Texas A&M), A. Pope (NOAO), D. Riechers (Caltech), J.R. Rigby (OCIW), J.D. Smith (Toledo), G. Stacey (C...
Systemic sclerosis (SSc) is a connective tissue disease that is characterized by tissue fibrosis, microvasculopathy, and autoimmunity. Interstitial lung disease (ILD) is a common complication of SSc and is one of the frequent causes of mortality in SSc. Although the exact etiology of SSc remains unknown, clinical and experimental investigations have suggested that genetic and environmental fact...
Sparse Subspace Clustering (SSC) has been used extensively for subspace iden-tification tasks due to its theoretical guarantees and relative ease of implemen-tation. However SSC has quadratic computation and memory requirementswith respect to the number of input data points. This burden has prohibitedSSCs use for all but the smallest datasets. To overcome this we propose a n...
OBJECTIVE SSc is characterized by microvascular abnormalities and leucocyte infiltration. Previous studies have suggested a proadhesive phenotype in SSc skin, but the functional consequences of this phenotype are not fully understood. Molecules known to mediate leucocyte adhesion include those present at intracellular junctions, such as junctional adhesion molecule-B (JAM-B), JAM-C and CD99, as...
زمینه و هدف: سیستمیک اسکلروزیس(SSc) یا اسکلرودرمی، یک بیماری مزمن بافت همبند با اتیولوژی نامشخص است. این بیماری مزمن با تغییرات عروقی، اختلالات سیستم ایمنی و فیبروز ارگان‌های داخلی مشخص می‌‌گردد. گرفتاری ریوی به‌صورت (Interstitial Lung Disease) ILD، یک درگیری شایع و علت اصلی مرگ در بیماران SSc می‌باشد. تاکنون هیچ درمان مؤثری برای بیماری مشخص نشده است. براساس شواهدی که التهاب را عامل اولیه ...
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