unstimulated whole salivary p53 was evaluated in non-involved subjects, in patients suffering from oral lichen planus (olp) and squamous cell carcinoma (scc). a total of 34 patients with olp, 24 patients suffering from oral scc and 41 non-involved participants were enrolled. the unstimulated whole saliva p53 level was assayed by elisa. data was analyzed by anova followed by the tukey post hoc t...

Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC) that occurs preferentially in the upper aerodigestive tract. We present two cases of BSCC, one arising in the conjunctiva and the other arising in a paranasal sinus. Clinical and pathological findings in these two cases, including immunohistochemistry is presented along with brief discussio...

Lung carcinoma with a basaloid pattern (BC) is classified as either a basaloid variant of squamous cell carcinoma (SCC) or as variant of large cell carcinoma (LCC) depending on the presence of a squamous component. In a previous study of 37 cases, the present authors showed that BC presented with a shorter median and overall survival. In order to confirm its clinical significance in a larger se...

Carcinoma associated fibroblasts (CAFs) have recently been implicated in neoplastic progression, tumor growth, angiogenesis, and metastasis. This special fibroblast subpopulation plays a major role in initiation of tumor progression of head and neck squamous cell carcinoma. We established a co-culture model of SCC-25 lingual squamous cell carcinoma cells and periodontal ligament fibroblasts. Ge...

INTRODUCTION Keratoacanthoma is a fast-growing crateriform skin tumor. Approximately 25% of such tumors undergo malignant transformation and develop areas of squamous cell carcinoma (SCC). The presence of laminin-322 has been associated with progression to invasive forms of SCC. The aim of this study was to determine whether or not immunohistochemical staining for laminin-322 would be of value ...

        Abstract   Squamous cell carcinoma (SCC) is the most common malignant tumors of oral cavity. The ratio of men to women is about 2: 1. Generally, it   is admitted that 60% of carcinoma of the mandibular gingival are located in the posterior of premolars. Gingiva is one of the less common sites of oral squamous cell carcinoma (OSCC). Due to the variable clinical and behavioral presentatio...

Basaloid squamous cell carcinoma (BSCC) of the colon is rarely found proximal to the anal canal. We report a case of an 81-year-old woman who was diagnosed with squamous cell carcinoma (SCC) of the lung without metastasis and BSCC of the sigmoid with differing histologic findings suggesting that these tumors were separate primary neoplasms. SCC of the colon has a dismal prognosis. Surgery is th...

skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...

a primary intraosseous carcinoma (pioc) is a squamous cell carcinoma arising within the  jawbone andshould be differentiated from a malignant ameloblastoma.  it  is not due to arising from an odontogenic cyst or tumor. the possibility of the lesion being  a metastasis fromanotherprimary site should be considered, and excluded by a careful history and examination. the diagnosis of a pioc is rare...