introdouction: oral squamous cell carcinoma (oscc), the most common form of oral cancer, requires early diagnosis and suitable treatments. fascin is a protein involved in cell adhesion and is increased in expression in certain types of carcinomas. the present study was conducted to assess fascin expression in oscc using an immunohistochemical technique. materials and methods: in the present ret...

Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographical locations. In this study, neoplasms from Turkmen Sahra, a region in Golestan province in northeast part of Iran, with a high incidence of squamous cell carcinoma were analyzed for the presence of HPV DNA. Turkmen Sahra is located in the cancer...

skin cancer has a broad and burdensome impact on the health and well-being of iranian and account for substantial health care costs to the nation. the first most common form of skin cancer is basal cell carcinoma (bcc); followed by the squamous cell carcinoma (scc) and the incidence of malignant melanoma (mm) is lower but is fatal. kaposi sarcoma (ks) is a tumor caused by human herpes virus 8. ...

background and objective: basal cell carcinoma (bcc) and squamous cell carcinoma (scc) are two common tumors of the skin. in some cases, distinction between bcc and scc can be difficult. this study aimed to clarify this uncertainty through immunohistochemical analysis. in this respect, epithelial membrane antigen (ema) and ber-ep4 are the two immunohistochemical markers on which we focus in dif...

purpose: to define the demographic and clinical features of eyelid masses at a referral hospital over a 10-year period. methods: this is a retrospective record-based study on patients with eyelid masses during the above-mentioned period. data on epidemiologic and clinical features and therapeutic approaches were collected and analyzed. results: 551 patients were included in the study from which...

Transformation of differentiated thyroid cancer into poorly differentiated carcinoma is rare. This report describes a case in which preoperative fine needle aspiration suggested a squamous cell carcinoma whereas needle core biopsy favoured an undifferentiated carcinoma of probable thyroid origin. Histology of the subsequent total thyroidectomy specimen revealed a biphasic tumour comprising area...

Acantholytic squamous cell carcinoma (SCC) is a rare vanant of squamous cell carcinoma and few cases have been reported in literature. Initially this tumour was considered to have a sweat gland origin by Lever in 1947 and was called Adenoid acanthoma of sweat gland. However, later it was accepted as an uncommon variant of squamous cell carcinoma synonyms acantholytic squamous cell carcinoma, ad...

Salivary gland tumors, the second most common neoplasm of the mouth after squamous cell carcinoma, account for a significant proportion of tumors of the oral and perioral regions. An unusual case of adenoma presented as a solitary intraoral palatine mass in a 32-year-old woman is reported here. The tumor was interpreted as an unusual pleomorphic adenoma because of the presence of exuberant squa...

We examined 170 formalin-fixed paraffin-embedded samples from esophageal squamous cell carcinoma patients. All subjects live in Mazandaran province, a region with high incidence rate of esophageal cancer and have become known as the “Asian Esophageal Cancer Belt”. Samples were tested for HPV-DNA by MY09/11 and Gp5+/6+ general primers using nested PCR. Of the 170 ESCC samples, 86 (50.6%) were ma...