background: the purpose of this study was to evaluate antileishmanial effects of asa via no pathway in leishmania major infected balb/c mice. moreover, toxicity and pathological consequences of asa administration were investigated. methods: balb/c mice were infected with l. major and asa was inoculated orally after lesion appearance for its ability to modulate no and to modify leishmania infect...

BACKGROUND Regional variations in size and parenchyma echo-texture of the spleen among sickle cell disease (SCD) patients have been documented in various publications. The objectives of this study were to assess the size and parenchyma echo-texture of the spleen of SCD patients and ascertain the relationship of age, height and weight with the spleen sizes. METHODS This was a cross sectional s...

Sixty spleens were observed according to the size of the splenic hilus depending on the size of the human spleen. The diameter and area of the lumina of the arterial branches were measured in 30 casts of the vascular bed of the spleen. Results were statistically evaluated, tabelated and graphed.

That a hemolytic process is one of the potential causes of anemia in cirrhosis of the liver has been well established by repeated demonstrations of decreased red cell survival time in a large proportion of patients (1-7). Shortened survival has been noted, not only with autologous cells, but also with transfused normal donor cells (1, 2). This would clearly establish the existence of an extraco...

A striking correlation between the capacity of an antigen to nonspecifically suppress humoral immune responses of subsequently administered antigens which are non-cross-reacting, i.e. to manifest antigenic competition and produce enlargement of spleen size through cell proliferation, was found. Increase in spleen size was always accompanied by a drop in the normal proportion of thymus-derived c...

most common tumors of the spleen are hematologic and lymphoid malignancies. non-lymphoid and non-hematologic tumors of the spleen are very rare, the most common of which are vascular tumors. this group of tumors in the spleen is composed of heterogeneous tumors such as hemangioma, angioendothelioma (ae), littoral cell angioma, and angiosarcoma. there are several histologic forms of ae such as e...

Aims: 1) To establish the volume, weight and size of a normal pancreas, spleen and kidney in 114 adult male autopsies; 2) To investigate the relationship between the volume, weight, and size of the pancreas, spleen, and kidney with body mass index (BMI), body surface area (BSA), age, height, and weight. Methods: The normal pancreas, spleen, and kidney volume, weight, and size retrospectively ga...

BACKGROUND It is unknown whether the spleen size correlates with disease severity and outcome in patients with idiopathic and heritable pulmonary arterial hypertension (PAH). OBJECTIVES To determine the prevalence of splenomegaly in PAH and assess whether it correlates with severity of disease and outcome. METHODS We identified subjects with either heritable or idiopathic PAH who had Dopple...