Nowadays, whenever is possible and as an alternative to open spine surgery, minimally invasive procedures are preferred treat spinal cord injuries (SCI), with percutaneous injections or small incisions, that faster, less traumatic, require recovery time. Injectable repair systems based on materials can be injected in the lesion site, eventually loaded drugs even cells, act scaffolds for repair....

serial light microscopy 765/494-7600 registration 765/494-7605 fax 2 SUMMARY The pathology of mammalian spinal cord injury (SCI) is usually defined as "central hemorrhagic necrosis", where variable amounts of the peripheral white matter is spared while the central grey matter deteriorates. This condition had traditionally made microinvestigation of the injury site in experimental animal models ...

Acute spinal cord injury (SCI) is one of the most common causes of severe disability and mortality after trauma. Magnetic resonance imaging (MRI) can identify different levels of SCI, but sometimes unable to detect the associated soft tissue injuries. The role of MRI with contrast in patients with SCI has not been studied. This is the first study in human to compare the efficacy of MRI with and...

OBJECTIVES To assess the prevalence of carbohydrate and lipid disorders in adults with chronic spinal cord injury and evaluate their risk contribution to cardiovascular diseases and the potential impact of exercise and pharmacologic and dietary therapies to alter these disorders and reduce cardiovascular disease risk. DATA SOURCES MEDLINE (PubMed), Cochrane Database and Web sites of the Ameri...

  Background :Cell-based therapies can be used to treat neurological diseases and spinal cord injuries. The aim of this study was to assess the clinical outcome of bone marrow derived mononuclear cells (BM-MNCs) transplantation in patients with spinal cord injuries.   Method s: Following a systematic review to detect clinical intervention studies, a meta-analysis was done for pooling data to es...

BACKGROUND The paucity of published reports from West Africa on the outcome of spinal cord injuries (SCI) reflects the limitations of the developing health care delivery system in this part of the world. OBJECTIVE To review the outcome of the spinal cord injuries managed in our centre and relate same to those of published reports. METHODS We conducted a prospective study by utilizing a stru...

One of the biggest problems of spinal cord injuries (SCI) is neuropathic pain. Moreover, it is pointed out by several studies as one of the major difficulties for SCI patients. Nowadays, the current challenge is to understand the etiology of the neuropathic pain in SCI patients. The objective of this study is use from quantitative clinical trials to observe the differences between spinal cord i...

Spinal cord injuries are commonly studied by causing injury to in vivo rodent spinal cords and analyzing histological and behavioral results post injury. However, very few researchers have investigated the dynamic behavior of the in vivo spinal cord during impact. This information would help to define relationships between impact parameters, internal structure deformation (such as grey and whit...

background and aims: one of the most common injuries around the world is the traumatic injury of the spine and spinal cord with unknown worldwide situation of traumatic spinal cord injury (tsci) affecting on the effectiveness of preventive policy programs. in addition, because of possibility of making paralysis, the potential injury to the spine could be one of the most important traumas and a ...

spinal cord injury (sci) is a devastating condition with enormous personal and social costs. to develop preventive strategies, the determination of epidemiological features and causes is required. due to iran's high incidence of road traffic crash (rtc) injuries, epidemiologic data concerning specific causes of sci may assist in reducing this national health dilemma. in a retrospective stu...