Our laboratory has been utilizing the Escherichia coli outer membrane protein LamB to study the mechanism of protein localization. Various lines of evidence suggest that, in addition to a signal sequence, regions within the mature protein are required for efficient localization. In particular, studies using LamB-LacZ hybrid proteins have identified regions between amino acids 27 and 49 of matur...

| Damage detection using guided Lamb waves is an important tool in Structural health Monitoring. In this paper, we outline a method of obtaining Lamb wave modes in composite structures using two dimensional Spectral Finite Elements. Using this approach, Lamb wave dispersion curves are obtained for laminated composite structures with different fibre orientation. These propagating Lamb wave modes...

ANAMNESIS We report about a 60-year-old woman with hepatopulmonary syndrome. The patient suffered from progressive dyspnea and liver cirrhosis following viral hepatitis C, acquired through blood transfusion 30 years ago. EXAMINATION RESULTS Remarkable were clinical signs of chronic liver disease (cutaneous spider naevi, palmar erythema) and signs of chronic respiratory failure (clubbing) with...

We study the survival of a single diffusing lamb on the positive half line in the presence of N diffusing lions to the right of the lamb and a haven at x = 0. If the lamb reaches this haven before meeting any lion, the lamb survives. We investigate the survival probability of the lamb, SN (x,L), as a function of N and the respective initial positions of the lamb and the lions, x and L. We deter...

Signal sequences function in protein targeting to and translocation across the endoplasmic reticulum membrane. To investigate the structural requirements for signal sequence function, chimeras of the Escherichia coli LamB signal peptide and prolactin were prepared. The LamB signal peptide was chosen by virtue of the extensive biophysical and biological characterization of its activity. In vitro...

The current study examined the role of thought suppression in spider phobia. Spider phobic (n = 41) and non-phobic (n = 40) subjects were asked to monitor their thoughts for three 5 min periods. During the first period, all subjects were instructed to "think about anything". During the second period, half of the subjects received suppression instructions (i.e., subjects were explicitly asked "n...

This paper presents an immobilization-based control method for spider-like robots that move quasistatically in tunnel environments. The control method is based on an immobilization theory which ensures that when a spider-like mechanism is bracing against the environment at an immobile posture, the naturally occurring compliance at the contacts stabilizes the mechanism as a single body. Based on...

UCLA scientists Katharina Kircanski, Matt Lieberman, and Michelle Craske demonstrated the power of words for people with a professed spider phobia. The experiment went something like this: First, the spider phobics were asked to stand outside next to a Chilean rose-haired tarantula (donʼt worry, it was in a container). People were encouraged to approach the spider little by little. On the first...

The appearance of newly induced LamB protein at the cell surface of Escherichia coli was followed topographically by immuno-electron microscopy. LamB protein was induced in E. coli wild-type or lac-lamB cells for a short period of time (4 to 6 min), such that the overall level of LamB protein in induced cells was at least twofold higher than that in uninduced cells. Antibodies bound to LamB pro...

a four- year-old moghanian breed ewe was admitted to the large animal veterinary clinic, university of tabriz due to dystocia. during obstetrical examination, it was revealed that the cervix has been closed firmly and vagina protruded about 5 cm through the vulva (vaginal prolaps). based on clinical findings and for saving the dam and lamb(s), the cesarean section was done. a normal alive femal...