Differentiated thyroid carcinoma (DTC) usually behaves in an indolent manner with low metastatic potential. The major sites of distant metastases are the lung and bone. Metastases to the brain, eye, breast, liver, kidney, muscle and skin are rare or relatively rare. These metastases have almost always appeared in patients with advanced disease and are often associated with poor prognosis but ov...

Urine bladder diverticula are usually asymptomatic, therefore they are incidentally diagnosed during examinations for other purposes. A Chinese patient, with a history of pulmonary adenocarcinoma first underwent a technetium-99m methylene diphosphonate whole-body bone scan. In addition to multiple skeletal metastases, abnormal shape of the urine bladder was also noted, which overlapped the supe...

Parkinson 's disease (PD) is characterized by progressive loss of dopaminergic neurons in the nigrostriatal pathway, but this seems to constitute only part of the whole pathological process of the disease. Accumulating data have documented the concomitant degeneration of other dopaminergic pathways and of the serotonergic, cholinergic and noradrenergic neurotransmitter systems. In addition,...

Dopa-responsive dystonia (DRD) is a genetic disorder characterized by childhood onset dystonia, dominant inheritance, diurnal symptoms fluctuation and positive levodopa response. Adult-onset DRD is frequently combined with parkinsonism and can be mistaken with young onset Parkinson's disease (YOPD). Both conditions are caused by dopamine deficiency, due to nigral cells' loss in YOPD, and due to...

Summanr Low-density lipoprotein (LDL) uptake in gliomas was studied to find out if LDL has potential as a drug camrer of boron. especially for boron neutron capture therapy. Single photon emission tomography (SPET) was performed 2 h and 20 h after intravenous injection of autologous 9"9Tc-labelled LDL in four patients with untreated and five patients with recurrent glioma. 9'Tc-LDL uptake was c...

1399) Topology of the potential energy surface (PES) along the PT and ET reaction coordinates (q p and q e) predicted by the theory with no solvent overlap (q e and q p orthogonal,) and at the condition pH = pK a (AH) and E applied = E CPET = E ET. The solvent overlap ̅ í µí¼† = 0 quantifies the coupling between the solvent modes along the PT and ET reaction coordinates. The SPET is kinetically ...

Neurochemical transmission is a fundamental element of brain organisation that has been relatively unexplored in the living human brain. Continuing advances in radionuclide imaging, particularly positron emission tomography (PET) and single photon emission tomography (SPET), mean that elements of neurochemical transmission can now be directly measured in vivo. With these techniques convincing a...