Introduction: Treatment efficacy of radiation therapy using Yttrium-90 radionuclide is evaluated by the bremsstrahlung SPECT imaging following radiation therapy. The radioisotopic images have the ability to provide reliable activity map of 90Y distribution. But these images have a low quantitative accuracy in the 90Y bremsstrahlung SPECT imaging, therefore the optimization of...

Objective: A novel multifocal collimator, IQ-SPECT (Siemens) consists of cardio-centric and 3D iterative SPECT reconstruction and makes it possible to perform MPI scans in a short time. The aims are to delineate the normal uptake in thallium-201 (Tl) SPECT in each acquisition method and to compare the distribution between new and conventional protocol, especially in patients with normal imaging...

Introduction: In nuclear medicine, the use of a pixelated semiconductor detector such as CZT is an of growing interest for introducing new devices. Especially, the spatial resolution can be improved by using a pixelated parallel-hole collimator with equal holes and pixel sizes based on the pixelated detector. The purpose of this study was to compare the effect of pixelated and ...

PURPOSE AND METHODS The noninvasive microsphere (NIMS) method quantifies cerebral blood flow with N-isopropyl-p-[123I]-iodoamphetamine (123I-IMP) without blood sampling of a patient, but when a fan beam collimator is used for collecting raw data in single photon emission computed tomography (SPECT), the procedure is complicated because we have to change the collimator. In phantom and clinical s...

BACKGROUND Cardiac 123I-meta-iodobenzylguanidine (MIBG) uptake is quantified using the heart-to-mediastinum ratio (HMR) with an Anger camera. The relationship between HMR determined using D-SPECT with a cadmium-zinc-telluride detector and an Anger camera is not fully understood. Therefore, the present study aimed to define this relationship using images derived from a phantom and from patients....

Background: Obtaining high quality images in Single Photon Emission Tomography (SPECT) device  is the most important goal in nuclear medicine. Because if image quality is low, the possibility of making a mistake in diagnosing and treating the patient will rise. Studying effective factors in spatial resolution of imaging systems is thus deemed to be vital. One of the most important factors in S...

OBJECTIVE A novel multifocal collimator, IQ-SPECT (Siemens) consists of SMARTZOOM, cardio-centric and 3D iterative SPECT reconstruction and makes it possible to perform MPI scans in a short time. The aims are to delineate the normal uptake in thallium-201 ((201)Tl) SPECT in each acquisition method and to compare the distribution between new and conventional protocol, especially in patients with...

A long bore fan beam collimator for imaging the head was designed and constructed for a SPECT system with a rotating scintillation camera. In order to avoid the patient's shoulder during rotation of the camera with a thick camera housing, the long bore design is necessary to allow the collimator to get close to the patient's head for improved spatial resolution. Operating at the minimum radius ...

BACKGROUND The purpose of the study is to evaluate whether a pinhole collimator is better adapted to bremsstrahlung single photon emission computed tomography [SPECT] than parallel-hole collimators and in the affirmative, to evaluate whether pinhole bremsstrahlung SPECT, including a simple model of the scatter inside the patient, could provide a fast dosimetry assessment in liver selective inte...

BACKGROUND Post-therapy SPECT/CT imaging of 90Y microspheres delivered to hepatic malignancies is difficult, owing to the continuous, high-energy Bremsstrahlung spectrum emitted by 90Y. This study aimed to evaluate the utility of a commercially available software package (HybridRecon, Hermes Medical Solutions AB) which incorporates full Monte Carlo collimator modelling. Analysis of image qualit...