introduction: estrogen is one of the gonadal hormones that has multiple beneficial actions in central nervous system and involves in learning and memory. alzheimer's disease (ad) is a progressive neurodegenerative disorder that impairs patient memory. the human nucleus basalis of meynert (nbm) is severely affected in alzheimer's disease. so in this study the effect of peripheral (intr...

materials and methods in this experimental study, nmri male mice were placed in groups receiving atropine (0.1 and 1 mg/kg), recipient of mgo-n (1, 2.5, and 5 mg/kg) and groups receiving atropine in effective dose and different doses of mgo-n were used. saline was used as a vehicle for drugs in the control groups. memory was evaluated with a step-down apparatus to determine the coming down late...

objective: the present study aimed to compare prospective and retrospective memory impairment and attention deficit in people suffering from chronic low back pain with those cognitive functions in healthy subjects. furthermore, this study examines the relation between severity and duration of pain and prospective and retrospective memory impairment and attention deficit. methods: the research w...

objective(s): there is controversial evidence about the effect of methamphetamine (meth) on spatial memory. we tested the time- dependent effects of meth on spatial short-term (working) and long-term (reference) memory in meth –sensitized and withdrawn rats in the morris water maze. materials and methods: rats were sensitized to meth (2 mg/kg, daily/5 days, sc). rats were trained in water maze ...

the central cholinergic system has been associated with cognitive function and memory and acetylcholine plays an important role during the early stages of memory consolidation. in this study, after training mice were tested with one way active avoidance procedure and retention were tested at 4, 8, 12, 16 and 24 hours of training and compared with non-shocked mice, in which it took 24 hours, a s...

abstract: introduction & objective: the hippocampal formation is a part of limbic system that plays an important role in memory and learning. the hippocampus is divided into three subfields: ca1, ca2 and ca3. in addition to pyramidal neurons and interneurons, the astrocytes play important roles in hippocampus, probably in memory and learning. in fact, learning needs some instruments for informa...

Introduction: Age-related cognitive decline or cognitive aging is largely the result of structural and functional decline in specific areas of the brain, but lifestyle also contributes to this cognitive decline. The aim of this study was to investigate the effect of working memory rehabilitation on visual memory and memory span in ageing.  Methods: This was a quasi-experimental study with pret...

introduction: recent studies suggest that glucocorticoids modulate memory reconsolidation. moreover, cholinergic system is involved in memory reconsolidation. since glucocorticoids interact with brain cholinergic system in modulating memory processing, we investigated whether glucocorticoid influences on the reconsolidation of emotionally arousing training depend on the cholinergic system. meth...

williams, watts, macleod and mathews' (1988) model of anxiety and depression leads to the prediction that anxious patients will show mood – congreuent implicit memory bias, while depressed patients will show mood-congruent explicit memory bias.although this prediction has been supported by some researchers (denny & hunt, 1992 mathews, moog, et al , 1989 watkins, et al, 1992), the reliabili...