CLINICAL SUMMARY Mediastinal enlargement and a solitary pulmonary nodule were detected on a 68-year-old male patient’s chest radiograph during routine annual examination. Computed tomography and magnetic resonance imaging revealed a lobulated, solid, and well-demarcated right paratracheal mass 6 3 4 3 4 cm in dimension (Figure 1). The solitary, heterogeneous parenchymal mass located in the righ...

This review describes the frequency of solitary thyroid nodules and their relationship to thyroid cancer. The importance of selecting patients appropriately for surgical excision is stressed. The factors predisposing to nodule formation and to a nodule being malignant are reviewed with emphasis that prior radiation exposure does not appear to increase the likelihood that a given nodule harbors ...

Patients with anterior neck masses commonly present to otorhinolaryngology clinics, but there are limited differential diagnoses for such lesions. Common ones include thyroid nodule and thyroglossal duct cyst. In an elderly patient, a differentiated thyroid carcinoma should be suspected especially if it moves with swallowing. We encountered a typical presentation of a solitary thyroid nodule-li...

N Eng J Med 2004;351:1764-71. Copyright © 2004 Massachusetts Medical Society. A 42-year-old woman presents with a palpable mass on the left side of her neck. She has no neck pain and no symptoms of thyroid dysfunction. Physical examination reveals a solitary, mobile thyroid nodule, 2 cm by 3 cm, without lymphadenopathy. The patient has no family history of thyroid disease and no history of exte...

BACKGROUND AND PURPOSE Accurate imaging characterization of a solitary thyroid nodule has been clearly problematic. The purpose of this study was to evaluate the role of the apparent diffusion coefficient (ADC) values in the differentiation between malignant and benign solitary thyroid nodules. MATERIALS AND METHODS A prospective study was conducted in 67 consecutive patients with solitary th...

The combination of autoimmune Graves’ disease with a solitary hot thyroid nodule suppressing the remainder of the thyroid gland is rare. We report a case of Graves’ disease associated with a single hyperfunctioning nodule with suppression of the remaining gland. A 45 year old male patient with past medical history of autoimmune Graves’ disease with severe ophthalmopathy was referred to endocrin...