Solid Lipid Nanoparticles (SLNs) have emerged as an alternative colloidal carriers for sustained release of lipophilic drugs with poor absorption and water solubility. This manuscript describes the effect of process variables on the production of Solid Lipid Nanoparticles (SLNs) from beeswax and carnauba wax and ketoprofen release from these carriers. It was found that by increasing drug co...

Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles. SLNs were developed to overcome the limitations of other colloidal carriers, such as emulsions, liposomes and polymeric nanoparticles because they have advantages like good release profile ...

The present review compiles the applications of lipid nanoparticles mainly solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the delivery of pharmaceutical actives. The attempts to overcome the low solubility and bioavailability of some drugs by their incorporation into lipid nanocarriers have been summarized. A special focus of this review is on different routes of ad...

As encapsulation of hydrophilic drugs in the solid lipid nanoparticles (SLNs) is still a challenging issue, the aim of this study was to prepare SLNs containing tramadol hydrochloride as a hydrophilic compound.The SLNs were prepared using glycerol monostearate (GMS), soy lecithin and tween 80 by double emulsification-solvent evaporation technique. The nanoparticles were optimized through a cent...

Abstract. We report on the magnetic characterization of Fe oxide nanoparticles by laser pyrolysis and the relationship between the preparation conditions and the magnetic response. It is shown that controlling the preparation conditions during the pyrolisis allows tuning the nanoparticles morphology and structure and consequently the magnetic properties of the nanoparticles. The nanoparticles a...

Interest in lipid based drug delivery has developed over the past decade fuelled by a better understanding of the multiple roles lipids may play in enhancing oral bioavailability. Moreover, the emergence of novel excipients with acceptable regulatory and safety profiles coupled with advances in formulation technologies have greatly improved the potential for successful lipid based formulations....