solid lipid nanoparticles (slns) have emerged as an alternative colloidal carriers for sustained release of lipophilic drugs with poor absorption and water solubility. this manuscript describes the effect of process variables on the production of solid lipid nanoparticles (slns) from beeswax and carnauba wax and ketoprofen release from these carriers. it was found that by increasing drug conten...

The development of vehicles for the co-encapsulation actives with diverse characteristics and their subsequent controllable co-delivery is gaining increasing research interest. Predominantly centred around pharmaceutical applications, majority such approaches have been focusing on solid formulations less so liquid-based systems. Simple emulsions can be designed to offer a microstructural platfo...

This research work deals with the design and development of solid lipid nanoparticles Losartan to improve solubility poorly soluble drug. are formed using hot homogenization technique followed by ultrasonication technique. Experiment trend is predicted standard calibration curve. The parameters studied percent drug release, entrapment efficiency, particle size SLN in-vitro release prepared SLN....

The use of nanoparticles as vectors for therapeutic agent delivery against COVID-19. In the image article number 20200155, Arun K. Iyer and co-workers have proposed utility different nanoparticle systems including polymeric nanoparticles, antibody-drug conjugates, solid-lipid siRNA-based technologies treating can be conjugated or encapsulated with potent anti-viral agents such remdesivir favipi...

objective(s): the aim of the present study was to prepare, characterize, and evaluate solid lipid nanoparticles (slns) containing zataria multiflora essential oil (zeo). materials and methods: in this study, z. multiflora essential oil-loaded solid lipid nanoparticles (ze-slns) were prepared to improve its efficiency in controlling some fungal pathogens. slns containing z. multiflora essential ...

Objective(s): In the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. Materials and Methods:Series of SLN were prepared using glyceryl monostearate, Tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (HPH) methods. SLN formulations were characterized ...

Nanoparticles are generally considered excellent candidates for targeted drug delivery. However, ion leakage and cytotoxicity induced by nanoparticle permeation is a potential problem in such drug delivery schemes because of the toxic effect of many ions. In this study, we have carried out a series of coarse-grained molecular dynamics simulations to investigate the water penetration, ion transp...

solid lipid nanoparticles of atovaquone (atq-sln) were prepared by high shearhomogenization method using tripalmitin, trilaurin, and compritol 888 ato as the lipidmatrices and phospholipon 90h, tween 80, and poloxamer 188 as the surfactants. optimizationof the formulations was conducted using 6 sets of 24 full-factorial design based on fourindependent variables that were the number of homogeniz...