Von Willebrand disease (VWD) is the most common inherited bleeding disorder, with an estimated prevalence ranging from 0.6% to 1.3% [1]. Therapies approved for VWD in the United States include desmopressin (eg, intravenous DDAVP®, intranasal Stimate®) and von Willebrand factor/factor VIII (VWF/FVIII) concentrates (Humate-P®, CSL Behring, Kankakee, IL; Alphanate® SD/HT, Grifols Biologicals, Los ...

The researches of cultivation winter wheat with application the biologically active substance potassium humate and nitrogen fertilizers different concentrations N 20 40 their interaction +GK showed that humate, without being a mineral fertilizer, increased crop capacity, content in grain, mass proportion grain protein, Grain nutrition quantity gluten were same as , had comparable values for pro...

Conductivity changes of dilute aqueous humic and fulvic acids solutions were monitored after the addition of small quantities of Cu, Cd, Pb, and Zn. The solutions were stirred at a constant and reproducible rate, and measurements proceeded until stable conductivities were attained. The values were compared to KCl reference solutions treated in an identical manner, and the results showed that th...

The structural and functional composition of humic acids in natural urbanized areas the European Far North Arctic has been studied using modern physical chemical research methods. It is shown that content fulvic for most soils higher than acids; soils, process humus formation humate (replantozem, pelozem humus-peat soil), humate-fulvate (turf soil, culturozem urbanozem) fulvate type (gleezem li...

INTRODUCTION Iliopsoas hemorrhage is a serious complication of bleeding disorders that occurs most commonly in patients with hemophilia and less commonly in patients with von Willebrand disease. It causes severe pain, muscle dysfunction and occasionally femoral nerve palsy. We describe the case of a patient with von Willebrand disease type 3 with a large iliopsoas hematoma who was treated with ...

Nickel (Ni) is a common and potentially toxic heavy metal in many fluvial ecosystems. We examined the potentially competitive and complementary roles of suspended sediment and a dissolved organic ligand, humate, in affecting the partitioning and toxicity of Ni to a model organism, Daphnia magna, in both batch and stream-recirculating flume (SRF) tests. Sediments included a fine-grained deposit,...

The article presents the results of research on peculiarities spelled yield formation and grain quality depending humate plant growth regulator use in conditions unstable moisture Forest Steppe Ukraine. purpose was to identify influence elements technology growing varieties productivity grain. During 2019–2022, conducted at experimental field educational production centre Bila Tserkva National ...

Fusarium wilt causes severe yield loss in greenhouse cucumbers. Humic substances refer to organic amendments typically applied the soil suppress pathogens and promote vegetable growth. The present study evaluated effects of two humic (humic acid (HA)) from weathered coal sodium humate peat (HN) on relative abundance oxysporum (F. oxysporum) cucumber HA HN showed different chemical structures as...