To cite: Bosman WM, Prakken FJ, Ritchie ED. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200866 DESCRIPTION A 59-year-old man presented to the emergency department after injuring the fourth digit of his right hand in an attempt to pick up a key on the other side of a steel rod fence. While leaning over the fence, he lost his balance, leading to a fall while...

Alterations of the collagen, the major structural protein in skin, contribute significantly to human skin connective tissue aging. As aged-appearing skin is more common in diabetes, here we investigated the molecular basis of aged-appearing skin in diabetes. Among all known human matrix metalloproteinases (MMPs), diabetic skin shows elevated levels of MMP-1 and MMP-2. Laser capture microdissect...

Background: Traction has been suggested to be an effective treatment for symptoms of neck disorder in patients with no contraindications. However, according to previous researches, the effectiveness of traction is controversial, particularly compared to other conservative treatments. This trial was conducted to evaluate the effect of sustained traction, using an over-the-door home cervical trac...

Compression therapy is frequently used to prevent hypertrophy of post-burn scars. This pilot study was performed in 6 patients to assess non-invasive changes induced in the tensile strength of the skin before any clinical improvement can be perceived. Assessments were performed using a computerized suction device delivering three 5 s cycles of 500 mbar depression. Measurements were made at one-...

objectives: to compare the outcomes of prone and supine lumbar traction in patients with chronic discogenic low back pain. methods: the test was prospective and randomized control trial. the structure of trial was urban physical medicine and rehabilitation clinic. participants was included of a total of 124 subjects with chronic low back pain (lbp) and evidence of a degenerative and/or herniate...

OBJECTIVES To determine the effects on urine calcium excretion of immobilization by skin traction in patients with pelvic fracture. METHODS In a prospective study, a consecutive series of patients with pelvic fracture treated by skin traction were enrolled. Serum (calcium, phosphorous, alkaline phosphatase, sodium, potassium, uric acid, BUN, creatinine) and fasting urine calcium, creatinine, ...

PURPOSE To identify if isolated surgical violation of the orbital septum predisposes to "middle lamellar" scarring and subsequent postblepharoplasty lower eyelid retraction. METHODS A retrospective review of patients who underwent transconjunctival blepharoplasty in either a postseptal (orbital septum undisturbed) or preseptal (septal incision required) plane was performed. Patients undergoin...

During wound healing of the skin, keratinocytes disassemble hemidesmosomes and reorganize their actin cytoskeletons in order to exert traction forces on and move directionally over the dermis. Nonetheless, the transmembrane hemidesmosome component collagen XVII (ColXVII) is found in actin-rich lamella, situated behind the lamellipodium. A set of actin bundles, along which ColXVII colocalizes wi...