نتایج جستجو برای: skin penetration
تعداد نتایج: 226549 فیلتر نتایج به سال:
It has previously been postulated that L-arginine emitted by penetrating Schistosoma mansoni cercariae serves as an intraspecific signal guiding other cercariae to the penetration site. It was suggested that penetrating in groups offers a selective advantage. If this hypothesis is correct and group penetration at one site on the host offers an advantage, it would follow that at such a site, suc...
Corresponding Authors: Kiran Sharma II E 96 / A, Nehru nagar, Ghaizabad, 201001, U.P. Email id: [email protected] Abstract: Skin penetration enhancers are the most commonly used approach for enhancing drug penetration into the skin through transdermal drug delivery system or topical administration. These skin penetration enhancers are molecules which reversibly remove the barrier resistance...
The ability of nanoparticles to penetrate the stratum corneum was the focus of several studies. Yet, there are controversial issues available for particle penetration due to different experimental setups. Meanwhile, there is little known about the mechanism and determinants of their penetration. In this paper the penetration of four model gold nanoparticles of diameter 6 and 15 nm, differing in...
The purpose of the study was to use a new type of in vivo animal model developed by our research group for the investigation of skin penetration, compared to the results of Franz cell measurements. The new in vivo experimental model provides possibility for the exact measurement of the quantity of the penetrated drug through the living mouse skin. Two gel formulations containing ibuprofen were ...
Abstract: Tolnaftate, an antifungal of thiocarbamate class, is used topically in 1% formulations. Its penetration into skin layers is a prerequisite for tolnaftate action against dermatophytes. The aim of this work was to optimize and validate a simple, rapid, accurate and reproducible procedure for tolnaftate assay in human skin samples and to apply this procedure for in vitro tolnaftate penet...
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