Hereditary nonpolyposis colorectal cancer is associated with defects in DNA mismatch repair. Here, we characterize tumor susceptibility of the recently described AfsA2-deficient mouse model. Within the first year of observation, all homozygous mice succumbed to disease, with lymphomas observed in at least 80% of the cases. The majority (70%) of animals 6 months or older developed intestinal neo...

Mastocytosis is one of eight subcategories neoplasms. Classification Myeloproliferative Tumors Lymphoid Tissues and hematopoietics 2008 the World Health Organization; a heterogeneous group myeloproliferative diseases that distinguished by excessive proliferation mast cells morphologically immunophenotypically atypical, in addition to accumulation these or more organs tissues, including skin, bo...

We describe the pathology in a captive adult White lipped treefrog (Litoria infrafrenata) with a squamous cell carcinoma of the skin and a free-living adult Common green treefrog (L. caerulea) with an adenocarcinoma of the skin. Although many amphibian neoplasms have been reported world wide, none had been described in Australian species.

© 2010 The Authors. doi: 10.2340/00015555-0739 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Paraneoplastic pemphigus (PNP) is an autoimmune bullous disease characterized by severe mucous membrane involvement, polymorphous skin eruptions, and underlying neoplasms. Most cases are associated with lymphoproliferative neoplasms, and solid tumours have rarely been associ...

Cutaneous extramedullary plasmacytomas (EMPs) are rare plasma cell neoplasms of the skin occurring in 2-4% of patients with multiple myeloma (MM). We describe a man diagnosed with IgA lambda MM (Stage III) after rapidly enlarging cutaneous nodules developed in the surgical site of recently excised skin malignancies. Cutaneous EMP must be considered for expanding cutaneous nodules at sites of su...

Background : Solitary fibrous tumours rare spindle cell neoplasms, initially regarded as occurring exclusively within the thoracic cavity with a pleural origin. We report an unusual and case, of solitary tumor skin. Whose evolution has been marked by several recurrences after surgical excision Case Report: 49 year old man, dorsolumbar cutaneous tumor.

Careful consideration must be given to the possibility of occult neoplasms in dermatomyositis in middle-aged to elderly patients.3,8,9 The most common cancers found in association with dermatomyositis are ovarian, pancreatic, and lung cancers. We have presented a case of dermatomyositis associated with cancer of the lung and presenting livedo reticulated ulcers due to livedoid vasculopathy. We ...

When treating childhood acute lymphoblastic leukemia (ALL), secondary neoplasms are a significant long term problem. Radiation is generally accepted to be a major cause of the development of secondary neoplasms. Following treatment for ALL, a variety of secondary tumors, including brain tumors, hematologic malignancies, sarcomas, thyroid cancers, and skin cancers have been reported. However, ol...

The authors describe the incidence of new primary cancers among 4,639 cases of squamous cell skin cancer (SCC) diagnosed between 1974 and 1994 in the cancer registries of the Swiss cantons of Vaud and Neuchâtel (total person-years at risk = 23,152). Overall, 729 metachronous cancers were observed versus 527.6 expected, corresponding to a standardized incidence ratio (SIR) of 1.4 (95% confidence...

Glomus tumors are neoplasms arising from the glomus body, which regulate skin temperature. They mostly benign and present in subungual area of a distal phalanx. However, they can occur extradigital location, may not be typical intradigital tumors. This makes it difficult to diagnose We report volar tumor mimicking painful ganglion with literature review.