A novel cross-linked honey hydrogel dressing was developed by incorporating Malaysian honey into hydrogel dressing formulation, cross-linked and sterilized using electron beam irradiation (25 kGy). In this study, the physical properties of the prepared honey hydrogel and its wound healing efficacy on deep partial thickness burn wounds in rats were assessed. Skin samples were taken at 7, 14, 21,...

Engineering skin substitutes provides a potential source of advanced therapies for the treatment of acute and chronic wounds. Cultured skin substitutes (CSS) consisting of human keratinocytes and fibroblasts attached to collagen-glycosaminoglycan substrates have been designed and tested in preclinical and clinical studies. Cell culture techniques follow general principles of primary culture and...

Done a lot of cases successfully in our place with bacteriophages small nonhealing chronic wounds but its use extensive infected burn wound healing is also encouraging. Our clinical evidence topical application on multi-drug resistant [MDR] bacterial has been done for the first time and never reported literature. The medical revolution horizon treating superbugs their positive effect economy es...

EROGLU, E., AGALAR, F., ALTUNTAS, I. and EROGLU, F. Effects of GlanulocyteColony Simulating Factor on Wound Healing in a Mouse Model of Burn Trauma. Tohoku J. Exp. Med., 2004, 204 (1), 11-16 ── The effects of burn trauma and granulocyte-colony stimulating factor (G-CSF) treatment on wound healing in a surgical incision model were studied. Sixty adult male mice were used in this study. Under gen...

Deep wounds, such as third-degree burns, often heal with disfiguring scars that are inelastic and lack sweat glands, oil glands, and hair follicles. Therapies that stimulate the regeneration of blood vessels in the wound could significantly improve the healing process, but remain elusive. Guoming Sun et al. (pp. 20976–20981) assessed whether a biodegradable, dextranbased hydrogel—a 3D network o...

PURPOSE To provide the physician and registered professional nurse with an overview of the pathophysiology and current management of burn injuries. TARGET AUDIENCE This continuing education activity is intended for physicians and nurses with an interest in learning about evidence-based prevention and management of burn wounds. OBJECTIVES After reading the article and taking the test, the pa...

BACKGROUND Burns are among the most prevalent injuries in humans with high cost in health care and heavy prolonged or permanent physical, psychological and social consequences. Commercial antimicrobial creams and dressing agents are unsuccessful in healing deep burn wounds. MATERIALS AND METHODS A study was conducted to assess the impact of crude linseed oil (LSO) topical application on burn ...

INTRODUCTION The skin protects against fluid and electrolyte loss. Burn injury does affect skin integrity and protection against fluid loss is lost. Thus, a systemic dehydration can be provoked by underestimation of fluid loss through burn wounds. PURPOSE We wanted to quantify transdermal fluid loss in burn wounds. METHOD Retrospective study. 40 patients admitted to a specialized burn unit ...

Background: Full-thickness burn injuries (FTBI) not only lead to a significant burden in multiple ways, including social life and self-esteem, but have also tremendous impact on environmental interaction by reducing sensibility manifold ways. On these grounds, possible ways solutions recover wounds are essentials should be overlooked. Methods: A review of experimental, clinical studies the rela...

The ability of Candida albicans to infect thermally injured mice was studied. Female mice were either left unburned or given a 20% total body surface area 2-s or 7-s scald burn. The wound or skin surface was then inoculated with a human burn wound isolate of C. albicans. At 4 h postburn, approximately 10(2) to 10(3) CFU/g of tissue could be recovered from the skin of burned and unburned animals...