Objective. Evaluate in postmenopausal women the effect of red clover extract (RCE) isoflavones over subjective status of skin, appendages, and several mucosal sites. Method. Postmenopausal women (n = 109) were randomly assigned to receive either two daily capsules of the active compound (80 mg RCE, Group A) or placebo of equal appearance (Group B) for a 90-day period. After a washout period of ...

On palpation, sub-mental bony spur was felt. The defect was associated with limitation of neck extension. Surgery was offered. At operation the extent of the sinus was about 4-6mm. The skin defect along with its cranial and caudal lesions was excised. The surgical wound was closed with multiple z-plasties (Fig. 2). The postoperative recovery was uneventful. Histopathology of the specimen showed...

INTRODUCTION: Vitiligo is an acquired autoimmune skin disease clinically manifested by foci of depigmentation due to the death epidermal melanocytes. Although vitiligo most often runs in isolation, being limited a pathological process skin, this can lead development number comorbid disorders. Alopecia areata also disorder appendages, one common disorders vitiligo, manifesting along with main di...

The factors that determine the axial orientation and phenotypes of skin appendages were analyzed by studying the effect of retinoic acid (RA) on embryonic chicken skin explant cultures. With RA uniformly distributed in the culture media, the feather buds became smaller, were disoriented or were transformed into scale-like structures in a concentration-dependent manner (from 0.05-2.5 microM). Wi...

Hair and nails are skin appendages that share with other ectodermal tissues a common developmental pathway. Inherited disorders affecting these two structures therefore very often involve other epithelial components and present with multiple anomalies, generating both physical and psychological distress among patients and their families. The present review briefly describes major recent advance...