With worldwide expansion of the aging population, research on age-related pathologies is receiving growing interest. In this review, we discuss current knowledge regarding the decline of skin structure and function induced by the passage of time (chronological aging) and chronic exposure to solar UV irradiation (photoaging). Nearly every aspect of skin biology is affected by aging. The self-ren...

BACKGROUND Nutritional factors play a key role in normal dermatologic functioning. However, little is known about the effects of diet on skin-aging appearance. OBJECTIVE We evaluated the associations between nutrient intakes and skin-aging appearance. DESIGN Using data from the first National Health and Nutrition Examination Survey, we examined associations between nutrient intakes and skin...

Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed. In the last years advanced glycation end products (AGEs) have received particula...

The microinflammatory model of skin aging is described. This model accounts for the loss of elasticity, resiliene and flexibility of the dermis, as well as for the appearance of wrinkles and for the thinning of the epidermis which are associated with aging. The lack of appropriate apparatuses for the correct measurements of skin hydration does not allow one to test this model for its predictive...

Skin aging is not a unique phenomenon but it is commonly divided into two different processes: chronological aging and photo-aging. Therefore we recognise two different phenotypes of skin aging. Chronological aging represents the structural, functional and metabolic changes in the skin that parallel the aging and degenerative changes in other body organs. Photo-aging is a consequence of oxidati...

With the increase in life expectancy, there is also growing interest in anti-aging treatments and technologies. The development of anti-aging functional drugs for the skin, and foods from natural sources, may offer solutions to this global matter. Aging involves structural, functional and biochemical changes that occur throughout cells and bodily tissues; the amount of hormones secreted from of...

Skin aging is a complex process, and a lot of efforts have been made to identify new and specific targets that could help to diagnose, prevent, and treat skin aging. Several studies concerning skin aging have analyzed the changes in gene expression, and very few investigations have been performed at the protein level. Moreover, none of these proteomic studies has used a global quantitative labe...

BACKGROUND Recently, we showed that outdoor air pollution exposure from traffic and industry is associated with an increased risk of skin aging in Caucasian women. In China, indoor air pollution exposure caused by the use of solid fuels like coal is a major health problem and might also increase the risk of skin aging in Chinese women. OBJECTIVE As cooking with solid fuels is a major source o...

Aim: Skin firmness is one of the key parameters to define skin quality and facial aging. Among minimally invasive anti-aging strategies, hyaluronic acid (HA) injection widely accepted improve quality. While most available HA injectables are designed intended for intradermal injection, a novel HA/sorbitol composition containing 2.6% high molecular weight stabilized by sorbitol was recently devel...

Background: The process of skin aging is a complex biological phenomenon consisting two components, referred to as intrinsic and extrinsic aging, respectively. There are currently several studies that research probiotics alternative therapeutic options for skin. Content: Skin in an individual combination aging. Intrinsic natural occurs with age, influenced by ethnicity, gender, gene, hormon, et...