With the aid of high resolution chromosome banding, a t(3;20) translocation was discovered in a large family with six retarded members. The translocation involved very small terminal segments. The unbalanced products resulting in partial trisomy 20q and monosomy 3p were observed in the retarded subjects. Gene localisation studies of the ADA gene, with a presumed locus on the long arm of chromos...

BACKGROUND The entomopathogenic mushroom Cordyceps militaris is an important medicinal and food resource owing to its various medicinal components and pharmacological effects. However, the high frequency of strain degeneration during subculture seriously restricts the large-scale production of C. militaris, and the mechanism underlying strain degeneration remains unclear. In this study, we arti...

The harmful effects of inbreeding can be reduced if deleterious recessive alleles were removed (purged) by selection against homozygotes in earlier generations. If only a few generations are involved, purging is due almost entirely to recessive alleles that reduce fitness to near zero. In this case the amount of purging and allele frequency change can be inferred approximately from pedigree dat...

Today’s market includes a penetrating segment commonly known as Generation X. This controversially complex cohort promises to give marketers a run for their money. Disagreement surrounding the segment is vast, encompassing everything from attitudes to more complex issues of their consumer attributes. Are they self-centered, demanding brats or savvy, welleducated individuals? In general, Generat...

This article reports key findings from the first phase of a research project investigating Net generation age students as they encounter e-learning at five universities in England. We take a critical view of the idea of a distinct generation which has been described using various terms including Net generation and Digital Natives and explore age related differences amongst first year university...

White sponge naevus occurred in association with coloboma of the iris in six members of one family, across three generations. The association of these two dominantly inherited conditions has not to our knowledge previously been described.