We describe a non-parametric bootstrap method to estimate the statistical properties of Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) images, whatever the type of noise in the projections and the reconstruction algorithm. Using analytical simulations and real PET data, this method is shown to accurately predict the statistical distribution, hence the ...

objective(s): in this study, we aimed to analyze the relationship between the diagnostic ability of fused single photon emission computed tomography/computed tomography (spect/ct) images in localization of parathyroid lesions and the size of adenomas or hyperplastic glands. methods: five patients with primary hyperparathyroidism (phpt) and 4 patients with secondary hyperparathyroidism (shpt) we...

We report a facile synthesis of bifunctional Fe3O4-Ag(125)I heterodimers for use as dual-modality imaging agents in magnetic resonance (MR) and single-photon emission computed tomography (SPECT). We introduced (125)I, which is a clinically used radioisotope, as a SPECT reporter, into Fe3O4-Ag heterodimer nanoparticles to provide a new type of bifunctional contrast agent for MRI and SPECT imaging.

We present a 55-year old male patient who was subjected to whole body skeletal scintigraphy for metastatic work up of urinary bladder cancer. Whole body 99mTc-methylene diphosphonate (MDP) skeletal scintigraphy was performed. That revealed no skeletal metastasis in the entire body skeleton and normally visualized left kidney with empty right renal fossa. Additionally tracer activity ...

Single-photon emission computed tomography (SPECT) has been a mainstay of nuclear medicine practice for several decades. More recently, combining the functional imaging available with SPECT and the anatomic imaging of computed tomography (CT) has gained more acceptance and proved useful in many clinical situations. Most vendors now offer integrated SPECT/CT systems that can perform both functio...

introduction: photon attenuation in tissues is the primary physical degrading factor limiting both visual qualitative interpretation and quantitative analysis capabilities of reconstructed single photon emission computed tomography (spect) images. the aim of present study was to investigate the effect of attenuation correction on the detection of activation foci following statistical analysis w...

Objectives This study aimed to determine the diagnostic accuracy of the 3 most commonly used noninvasive myocardial perfusion imaging modalities, single-photon emission computed tomography (SPECT), cardiac magnetic resonance (CMR), and positron emission tomography (PET) perfusion imaging for the diagnosis of obstructive coronary artery disease (CAD). Additionally, the effect of test and study c...

Objectives This was a phase II trial to assess flurpiridaz F 18 for safety and compare its diagnostic performance for positron emission tomography (PET) myocardial perfusion imaging (MPI) with Tc-99m single-photon emission computed tomography (SPECT) MPI with regard to image quality, interpretative certainty, defect magnitude, and detection of coronary artery disease (CAD) ( 50% stenosis) on in...

As part of their initial workup, patients typically undergo videoelectroencephalography (video-EEG), magnetic resonance imaging (MRI) of the brain, and neuropsychological testing [3]. Depending on how well these tests localize the epileptic foci, additional studies might be indicated, such as positron emission tomography (PET), magnetoencephalography (MEG), and single photon-emission computed t...

Background First pass myocardial perfusion imaging by CMR may permit the detection of myocardial ischaemia with greater accuracy than single photon emission computed tomography (SPECT). Technical developments have led to improvements in myocardial perfusion CMR, particularly through accelerated data acquisition methods. These permit the acquisition of data at higher spatial resolution than conv...