نتایج جستجو برای: single nucleotide polymorphisms
تعداد نتایج: 989640 فیلتر نتایج به سال:
allele frequencies of single nucleotide polymorphisms (snps) are variable among different populations; therefore the study of snps in ethnic groups is important for establishing the clinical significance of the screening of these polymorphisms. the main goal of the research is to study the polymorphisms of cyp2c9 , cyp2c19 , vkorc1 , and slco1b1 in yakuts. genomic dna from 229 yakut subjects we...
the purpose of this study was to determine the clinical significance of changes in the plasma adiponectin concentration in patients with bronchial asthma and to test the association between the single nucleotide polymorphisms (snps) rs2241766 and rs1501299 in the adipoq gene and bronchial asthma in the chinese li population.we selected 120 cases and 120 controls, and plasma adiponect...
Background: We explored the effect of vitamin D receptor gene (VDR) polymorphisms in response to PEG-IFN treatment in Egyptian chronic hepatitis B (CHB) patients. Methods: Two hundred hepatitis B virus (HBV) patients (42.3±10.7 years) on PEG-IFN α-2a (180 μg /kg for 48 weeks) and one hundred control subjects (37.3 ±12 years) were enrolled in the study. Vitamin D levels a...
GDF9 gene is one of the most important effective factors on litter size in sheep. Thus, the aim of the present study was to detect single nucleotide polymorphisms (SNPs) available in exon 2 of GDF9 gene in pure and crossbred of Pakistani sheep using PCR-SSCP. Hence, blood samples were collected from 30 Pakistani sheep, 17 crossbred sheep (Pakistani rams × Lori-Bakhtiari) and 7 crossbred sheep (...
The avianuncoupling protein (avUCP) is a member of the mitochondrial transporter superfamily that uncouples proton entry in the mitochondrial matrix from ATP synthesis. The polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method was used to estimate the allele and genotype frequencies of the UCP/HhaI polymorphisms and to determine associations between these polymorp...
We propose a Bayesian variable selection method in semi-parametric models with applications to genetic and epigenetic data (e.g., single nucleotide polymorphisms and DNA methylation, respectively). The data are individually standardized to reduce heterogeneity and facilitate simultaneous selection of categorical (single nucleotide polymorphisms) and continuous (DNA methylation) variables. The G...
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