PURPOSE 14-3-3 is a highly conserved, ubiquitously expressed family of proteins. At least seven mammalian isoforms (beta, epsilon, gamma, eta, theta, sigma, and zeta) are known. These proteins associate with over 200 different target molecules and activate several downstream signaling cascades involved in the regulation of metabolism, cell cycle, apoptosis, protein trafficking, transcription, s...

‎In this paper‎, ‎algebraic investigations on sup-$Sigma$-algebras are presented‎. ‎A representation theorem for‎ ‎sup-$Sigma$-algebras in terms of nuclei and quotients is obtained‎. ‎Consequently‎, ‎the relationship between‎ ‎the congruence lattice of a sup-$Sigma$-algebra and the lattice of its nuclei is fully developed.

in this paper, we define the common minimal common neighborhooddominating signed graph (or common minimal $cn$-dominating signedgraph) of a given signed graph and offer a structuralcharacterization of common minimal $cn$-dominating signed graphs.in the sequel, we also obtained switching equivalencecharacterization: $overline{sigma} sim cmcn(sigma)$, where$overline{sigma}$ and $cmcn(sigma)$ are ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 introduction: health care organizations have begun applying six sigma methods into their operations. on the other hand, the difficulty of using indicators to compare health care providers in a meaningful way has led to an increased focus on using information about “adverse events”- that is , events that should not happen i...

enterprise resource planning (erp) has become the most strategic tool for an organization to employ. a leading erp solution is sap®. it has been employed by organizations to enable them to collaborate on different projects and to integrate all aspects of operations. just as organizations have adopted erp solutions, they employed quality initiatives that are designed to help organizations maximi...

In this paper, by considering the notion of $Sigma$-hyperalgebras for an arbitrary signature $Sigma$, we study the notions of regular and strongly regular relations on a $Sigma$-hyperalgebra, $mathfrak{A}$. We show that each regular relation which contains a strongly regular relation is a strongly regular relation. Then we concentrate on the connection between the fundamental relation of $mathf...

Cyanobacteria are eubacteria that perform oxygenic photosynthesis like plants. The initiation of transcription, mediated by the RNA polymerase holoenzyme, is the main determinant of gene regulation in eubacteria. The sigma factor of the RNA polymerase holoenzyme is responsible for the recognition of a promoter sequence. In the cyanobacterium Synechocystis sp. PCC 6803, the primary sigma factor,...

This article provides an overview of present knowledge regarding the relationship between the cholinergic system and sigma-1 receptors, and discusses potential applications of sigma-1 receptor agonists in the treatment of memory deficits and cognitive disorders. Sigma-1 receptors, initially considered as a subtype of the opioid family, are unique ligand-regulated molecular chaperones in the end...

Plants contain nuclear-coded sigma factors for initiation of chloroplast transcription. The in vivo function of individual members of the sigma gene family has become increasingly accessible by knockout and complementation strategies. Here we have investigated plastid gene expression in an Arabidopsis (Arabidopsis thaliana) mutant with a defective gene for sigma factor 6. RNA gel-blot hybridiza...