This research pertains to the three-dimensional (3D) finite element analysis (FEA) of the stress intensity factors (SIFs) along the crack front in a spherical pressure vessel coated with functionally graded material (FGM). The vessel is subjected to internal pressure and thermal gradient. The exponential function is adopted for property of FGMs. SIFs are obtained for a wide variety of crack sha...

Stress-intensity factors (SIFs) are the most important parameters in fracture mechanics analysis of structures. These parameters are evaluated for a stationary crack in functionally graded plates of arbitrary geometry using a novel Galerkin based mesh-free method. The method involves an element-free Galerkin method (EFGM), where the material properties are smooth functions of spatial coordinate...

In this investigation, we successfully employed the Non-Uniform Rational B-spline (NURBS) to study fracture mechanics. NURBS functions are very popular in design field (CAD model) and it is used as an alternative Lagrange interpolation polynomials. The extended isogeometric analysis based on basis function evaluate stress intensity factors (SIFs) order control crack propagation. For various len...

We report our detailed metal-enhanced phosphorescence (MEP) findings using Rose Bengal at low temperature. Silver Island Films (SiFs) in close proximity to Rose Bengal significantly enhance the phosphorescence emission intensity. In this regard, a 5-fold brighter phosphorescence intensity of Rose Bengal was observed from SiFs as compared to a glass control sample at 77 K. In addition, several f...

Metal-Enhanced Fluorescence (MEF) effects from different density silver island films (SiFs) and the effects of far-field excitation irradiance on the observed enhancement of fluorescence were studied. It is shown that MEF non-linearly depends on silver nanoparticle (NP) size/density, reaching a maximum value for SiFs made at a deposition time (DT) of ∼5 minutes, i.e. just before SiFs become con...

Salmonella is an intracellular bacterial pathogen that replicates within a membrane-bound vacuole in host cells. The major lysosomal membrane proteins 1 and 2 (LAMP-1 and LAMP-2) are recruited to the Salmonella-containing vacuole as well as Salmonella- associated filaments (Sifs) that emerge from the vacuole. LAMP-1 is a dominant membrane marker for the vacuole and Sifs. Its colocalization with...

PicoGreen (PG) is a fluorescent probe for both double-stranded DNA (dsDNA) detection and quantification based on its ability to form a luminescent complex with dsDNA as compared with the free dye in solution. To expand the sensitivity of PG detection, we have studied the spectral properties of PG, both free and in complex with DNA in solution, when the fluorophore is in proximity to silver nano...

The aims of this study were to investigate the impact of soybean isoflavones (SIFs) on the cellular oxidative stress levels in hormone-sensitive type (LNCap) and hormone-insensitive type (DU145) of prostate cancer, and to elucidate the main components and their roles in the transformation of androgen dependency (AD)/ androgen independency (AI). The LNCap and DU145 cells were treated with differ...

In recent years, Fourier spectral methods have been widely used as a powerful tool for solving phase-field equations. To improve its effectiveness, many researchers have employed stabilized semi-implicit Fourier spectral (SIFS) methods which allow a much larger time step than a usual explicit scheme. Our mathematical analysis and numerical experiments, however, suggest that an effective time st...

Integrate and fire oscillators are widely used to model the generation of action potentials in neurons. In this paper, we discuss small noise asymptotic results for a class of stochastic integrate and fire oscillators (SIFs) in which the buildup of membrane potential in the neuron is governed by a Gaussian diffusion process. To analyze this model, we study the asymptotic behavior of the spectru...