because of possible increase in the incidence of brucellosis in the city ghom , serological and bacteriological studies were conducted to investigate the rate of infection in this city. a total of 819 blood samples from human , “suspected” cases were investigated (serologically) 121 of these were positive for brucellosis ,(14/6%).of 182 samples of milk collected from cattle 50 were positive (27...

background brucellosis is a zoonotic disease involving several organs with different presentations. it is primarily a disease of animals. human infection is usually acquired by close contact with infected animals or consumption of unpasteurized dairy products. the major reservoirs include goat, sheep, swine and cattle. human to human transmission of brucellosis is a rare entity, especially peri...

Brucellosis is a highly contagious zoonosis that affects the public health and economic performance of endemic as well as non-endemic countries. In developing nations, brucellosis is often a very common but neglected disease. The purpose of this review is to provide insight about brucellosis in animal populations in Egypt and help to understand the situation from 1986 to 2013. A total of 67 nat...

Competitive and standard enzyme-linked immunosorbent assays (ELISAs), rose bengal (RB), complement fixation, and agar gel immunoprecipitation with native hapten (AGID-NH) were compared by using sera from Brucella-free, Brucella melitensis-infected, and B. melitensis Rev1-vaccinated sheep. The most sensitive tests were indirect ELISA and RB, and the most specific tests were AGID-NH and competiti...

Brucella is ┙-Proteobacteria causing an infectious disease in mammals that could be transmitted to humans. Ruminant and swine are prone to be infected by such microorganism all over the world, thus acting as a potential reservoir for domestic livestock and therefore, affecting humans. Brucella species differ in their hosts’ preference, physiological abilities and cell surface structural charact...

An epidemiological survey was conducted in pastoral regions of Ethiopia to investigate the distribution of brucellosis in sheep and goats. Between November 2004 and December 2007, a total of 6,201 serum samples were collected from 67 randomly selected peasant associations, 25 districts and eight pastoral zones of Ethiopia. The Rose Bengal plate test (RBPT) and complement fixation test were used...

The use of a sensitive and quantitative radioimmunoassay has enabled much finer dissection of the immunoglobulin-antibody profiles for an individual immune response. The kinetics of the response are considered in relation to the switch from IgM to IgG antibody production. In the domestic fowl, the kinetics of this switch varied with different antigens: whereas the response to a thymus-dependent...

BACKGROUND Brucellosis is a zoonosis of veterinary, public health and economic significance in most developing countries. Human brucellosis is a severely debilitating disease that requires prolonged treatment with a combination of antibiotics. The disease can result in permanent and disabling sequel, and results in considerable medical expenses in addition to loss of income due to loss of worki...

Brucellosis infection is a multisystem disease, with a broad spectrum of symptoms. We investigated the existence of clusters of infected patients according to their clinical presentation. Using national surveillance data from the Electronic-Integrated Disease Surveillance System, we applied a latent class cluster (LCC) analysis on symptoms to determine clusters of brucellosis cases. A total of ...

BACKGROUND Brucellosis is an endemic infection in Georgia. We conducted a review of patient records with a suspected or confirmed diagnosis of brucellosis over three decades at the central referral hospital for brucellosis cases, the Institute of Parasitology and Tropical Medicine (IPTM) in Tbilisi. The purpose was to describe the demographic profile and clinical characteristics as well as diag...