OBJECTIVES Nearly one-third of healthcare costs are potentially avoidable and would not compromise medical care if eliminated. Therefore, we sought to evaluate the financial impact of reduction in use of creatinine kinase (CK)-MB and myoglobin tests after removing them from the cardiac enzyme order set at a community hospital. METHODS Grand rounds were held, and an email notification was sent...

Glycosmis pentaphylla (Rutaceae) are well known in India as Ashvashakota, Vananimbuka, Pathalagarudi (Sanskrit), Ban-nimbu (Hindi), Kirmira (Marathi) Golugu and Gongipadu (Telugu) of ethyl acetate and methanolic extracts (100, 200 and 400 mg/kg) was prepared and tested for its hepatoprotective effect against carbon tetrachloride induced in rats. Alteration in the levels of biochemical markers o...

A 67-year-old widow developed asthma in 1956 and had had eczema since her youth. Skin testing showed her to be sensitive to pollen; pets and many plants made her wheeze, and she was sensitive to penicillin. For the past five years she had experienced a tight substernal pain on exertion and had had one episode of paroxysmal atrial tachycardia but without evidence of a myocardial infarct. Two wee...

We studied the in-hospital mortality and morbidity of 745 patients who had suffered a first myocardial infarction. One hundred twenty-four patients (16.6%) had nontransmural infarction and 621 (83.4%) had transmural infarction. Both groups of patients were similar in the distribution of age, sex, and coronary risk factors. Patients with nontransmural infarction had a significantly lower mortali...

DIAGNOSTIC ENZYMOLOGY has grown exponentially since elevated serum amylase was first associated with pancreatitis in 19081 and Karmen, Wroblewski, LaDue, and their associates demonstrated in 1954 that SGOT* and LDH activity in serum increased following myocardial infarction.2 Following Markert's elucidation of the nature of LDH isoenzymes3 their importance in differential diagnosis was emphasiz...

Mice ingesting a standard rodent diet supplemented with polybrominated biphenyls (PBBs) were more susceptible to chlorinated hydrocarbon solvent-induced renal and hepatic damage, as well as the lethal effects of CHCl3 and CCl4, than were mice consuming control diet. As little as 0.025 ml/kg CHCl3 caused a significant increase in serum glutamic oxaloacetic transaminase (SGOT) and blood urea nitr...

Aim of the study was to evaluate the hepatoprotective activity of ethanolic seed extract of Lawsonia inermis against paracetamol induced liver damage in rats. Wistar albino rats of either sex were divided in to 5 groups of 6 each. The rats were intoxicated with paracetamol (750mg/kg) at every 72 hrs for 21 days. Silymarin (50mg/kg) and Lawsonia inermis (200 & 400 mg/kg) were orally administered...

Extract of Methanol:ethanol (70:30) of Prunus domestica was prepared and tested for its hepatoprotective effect against Paracetamol and CCl4 induced hepatitis in rats . Alteration in the levels of biochemical markers of hepatic damage like SGPT, SGOT, ALP,Total bilirubin, direct bilirubin and tissue LPO, GSH, catalase and SOD were tested in both treated and untreated groups. Paracetamol (2 g/kg...