background: to determine which radiotherapy parameters are associated with the tumor response of locally advanced non-small cell lung cancer (nsclc) patients undergoing concurrent chemoradiotherapy. materials and methods: thirty one patients with iiia/iiib nsclc underwent chemoradiotherapy with a median dose of 63 gy. on our actual treatments, we made radiotherapy planning to cover the planning...

objectives : squamous cell carcinoma (scc) is the most common malignant neoplasm of the oral cavity and a public health threat. tumor progression is believed to be influenced by angiogenesis as well as tumor cell proliferation; however, the correlation of these two factors in tongue scc still remains unclear. this study aimed to assess the correlation of these two factors in tongue scc. materia...

Unclassified mixed germ cell-sex cord-stromal tumor composed of germ cells and sex cord derivatives is a rare neoplasm. Approximately 10% of such tumors have malignant germ cell components. We report the case of a 28 year-old female with a right adnexal mass measuring 8 cm in greatest dimension, containing areas with both germ cell and sex cord components. The germ cell portion contained multip...

Abstract Interaction between tumor cells and neurons drives the progression of glioblastoma (GBM), which is characterized by enhanced immunosuppressive myeloid cell accumulation. Our previous results revealed that myeloid-derived suppressor subsets (MDSCs) play a critical role in tumorigenesis sex-specific manner, with monocytic MDSCs (mMDSCs) accumulating male tumors granulocytic (gMDSCs) corr...

Leydig cell tumor is a rare benign which belongs to the category of sex cord stromal tumors ovary. usually presents with androgenizing features like hirsutism, deepening voice, or clitoromegaly and are often suspected only if such symptoms present. can however be estrogenizing non-functional. We report an incidental finding in patient who underwent hysterectomy for postmenopausal bleeding.

purpose: to define the demographic and clinical features of eyelid masses at a referral hospital over a 10-year period. methods: this is a retrospective record-based study on patients with eyelid masses during the above-mentioned period. data on epidemiologic and clinical features and therapeutic approaches were collected and analyzed. results: 551 patients were included in the study from which...

A 12-year-old female with developmental delay/mental retardation and a family history of gynecologic cancers presented with nonspecific abdominal complaints and was found to have a 4.5-kg, 25- x 23- x 15-cm pelvic mass with solid and cystic components and associated retroperitoneal and mesenteric lymphadenopathy. Laboratory studies revealed increased serum levels of CA-125 and inhibin B. Histol...

Sertoli cell tumors of the testis are extremely rare tumors with a heterogeneous pathology. Three histological variants have been described: Sertoli cell tumor not otherwise specified (NOS), large cell calcifying sertoli cell tumor and the Sclerosing Sertoli cell tumor. The sclerosing Sertoli cell tumor described herein is associated with prominent stromal sclerosis. They present as painless...