Bypassing agents are the most commonly used medicines for the treatment of hemophilia patients with inhibitors. The aim of this study is to identify the cost components of management of bleeding vents in hemophilia patients with inhibitors in Iran. This study is a cross-sectional study using a bottom-up approach to determine the cost components of treatment of hemophilia patients with inh...

Patients with severe von Willebrand disease (VWD) may develop arthropathy after joint bleeds. Information on its prevalence and severity is limited. We aimed to assess the occurrence and severity of arthropathy in VWD and its impact on daily life. VWD patients with and without verified joint bleeds were matched for age, sex and Factor VIII level or von Willebrand Factor activity in a nested cas...

introduction: hemophilia is a hereditary disease with intraarticular hemorrhage as the most common manifestation of it. having taken into consideration the progressive articular degeneration, individual dysfunction, need for medical and surgical treatment, great cost to the patients, and also legal problems brought about by hemophilia patients’ dysfunction, this study examines the relationship ...

BACKGROUND Hemophilia is marked by frequent joint bleeding, resulting in pain and functional impairment. OBJECTIVE This study aimed to assess the reliability of five patient-reported outcome (PRO) instruments in people with hemophilia (PWH) in a non-bleeding state. METHODS Adult male PWH of any severity and inhibitor status, with a history of joint pain or bleeding, completed a pain history...

conclusions vaccination of non-immune individuals against hav infection in high risk groups especially hemophilia and thalassemia patients is recommended. results did not show any differences about seroprevalence of hev among iranian general population. results anti-hav igg antibodies were observed more frequently in thalassemia patients (60/64; 93.8%) than in hemophilia patients (104/155; 67.1...

Background The Pain, Functional Impairment, and Quality of Life study was an observational, cross-sectional assessment of the impact of pain on functional impairment and quality of life in adult people with hemophilia (PWH) of any severity in the USA who experience joint pain and/or bleeding. Objective To assess internal consistency (IC) and item-total correlation (ITC) of assessment tools us...

background: pain and limited range of motion (rom) are the crucial subsequent results of joint hemorrhages in individuals with bleeding disorders and hemophilia. exercise interventions are particularly recommended in treatment of such patients. the purpose of this study was to detect the influences of conventional exercise therapy and hydrotherapy on the knee joint complications in patients wit...

As hemophilia is a chronic bleeding diseaseand can interfere with daily performanceof children, these children require continuoustraining to prevent bleeding and take timely action(1). Since children nurses play an important role inthe education of involved children and their Selfefficacyand also due to today’s approach whichis using educational computer games, the use ofeducational games in re...