BACKGROUND Local biosynthesis of estrogens is thought to be important for the maintenance and growth of endometriotic implants. In addition to the formation of estrogen via the aromatase pathway, steroid sulphatase (STS), which is responsible for the hydrolysis of estrogen sulphates, may be an important source of estrogens in endometriosis. METHODS Eutopic and ectopic endometrial samples from...

Endometriosis is primarily characterized by the presence of tissue resembling endometrium outside the uterine cavity and is usually diagnosed by laparoscopy. The most commonly used classification of disease, the revised American Fertility Society (rAFS) system to grade endometriosis into different stages based on disease severity (I to IV), has been questioned as it does not correlate well with...

objective(s): the purpose of this study was to conduct a meta-analysis on human micrornas (mirnas) expression data of endometriosis tissue profiles versus those of normal controls and to identify novel putative diagnostic markers. materials andmethods: pubmed, embase, web of science, ovid medline were used to search for endometriosis mirna expression profiling studies of endometriosis. the mirn...

Endometriosis is a reproductive disease characterized by the growth of endometrial cells at sites outside the uterus. This disease is a serious disorder associated with chronic pain and infertility, which may be present in 6 million women in this country. Traditional medical therapy has consisted of hormonal regimens that limit the action of endogenous estrogen. The etiology of endometriosis is...

BACKGROUND & OBJECTIVE Endometriosis is one of the most commonly encountered benign problems in gynaecology. It is frequently associated with chronic pelvic pain, dysmenorrhoea, menorrhagia and dyspareunia, which lead to infertility. To determine the possible association between polychlorinated biphenyls (PCBs) and GSTM1 null (*0/*0) mutation and their possible impact in the pathogenesis of end...

Endometriosis is defined as presence of endometrial tissue outside of the uterus. It is a common disorder of women in reproductive age. It is estimated to occur in ten percent iof women in this age and even more in patients with infertility and pelvic pain. Endometriosis varies in appearance from a few minimal lesions to massive ovarian endometriotic cysts that distort the tubo-ovarian anatomy ...

Endometriosis is a common, complex gynecologic disorder characterized by the presence of endometrial-like tissues at extrauterine sites. Elevation in protein and lipid mediators of inflammation including oxylipins and cytokines within the peritoneum characterize the inflamed pelvic region and may contribute to the survival and growth of displaced endometrial tissues. The presence of a clinicall...

As the diagnosis requires a laparoscopy, we only have data in women with pain and/or infertility. Endometriosis has been considered to be single disease defined as ‘endometrium like glands and stroma outside uterus’. However, subtle, typical, cystic ovarian deep endometriosis lesions should different pathologies which occur all combinations severities. All large datasets, especially those based...

<span lang="EN-US">Machine learning is a cutting-edge technology used for predicting and diagnosing various diseases. Various machine algorithm facilitates the prediction. The decision tree belongs to that performs both classification constructs tree-like evaluate best features. well in prediction of Endometriosis recurrence disease creates an emotional impact women. lump-like structure a...

INTRODUCTION. Endometriosis is a disease characterized by the presence of tissue that is histologically identical to endometrium at ectopic locations outside the uterine cavity and protean manifestations. The incidence of endometriosis is strongly influenced by the awareness of non-classical lesions and because of the long-standing interest of the group in these lesions. The prominent symptoms ...