PURPOSE to evaluate the differences between the maternal and perinatal outcomes of pregnancies complicated by preeclampsia, according to the classification as the severe/mild form, and the early/late onset form. METHODS a retrospective study with 211 pregnancies complicated by preeclampsia, assessed at a university reference center from 2000 to 2010. The diagnosis and disease severity were ba...

Background: Preeclampsia is most common medical disordersduring pregnancy, and the rate of hypertension ranges from 5 – 8 % f or all types of pregnancy. There was a significant difference between cancer antigen -125, plasma fibrinogen and Creactive protein to the severity of preeclampsia. Objective: To determine the level ofserum CA-125 level, C-reactive protein and plasma fibrinogen in preecla...

Understand the effects of pregnancy on the maternal cardiovascular system. Devise a clear and rational plan for antepartum care in women with chronic hypertension. Understand the distinction between pregnancy-induced hypertension and preeclampsia, and between “mild” and “severe” preeclampsia. Discuss the risks and benefits of the various preventive strategies for women at highrisk for developin...

BACKGROUND To evaluate the soluble fms-like tyrosine kinase-1 (sFlt-1), placental growth factor (PlGF), and sFlt-1/PlGF ratio for the prediction of early- and late-onset preeclampsia in a high-risk cohort. METHODS We studied serial serum samples collected prospectively at 12+0-14+0, 18+0-20+0, and 26+0-28+0 weeks+days of gestation in 6 women who developed early-onset preeclampsia (before 34 w...

BACKGROUND Preeclampsia is a pregnancy complication with unknown etiology and its incidence is associated with genetic and environmental factors. There are inconsistent reports related to the role of endothelial nitric oxide synthase (eNOS) 4a/b polymorphism on the risk of preeclampsia development. The aim of the present study was to investigate the possible influence of eNOS 4a/b and its syner...

background and objective: the aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-crp) in preeclampsia and to compare hs-crp levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. materials and methods: serum hs-crp levels were investigated in 40 cases of normal pregnant women, 37 cases with mild preeclampsia and 38 cases...

BACKGROUND Liver X receptor alpha (LXRα) and endoglin have been postulated to play roles in trophoblast invasion and lipid metabolic disturbances. However, the relationship between LXRα and endoglin levels in serum and placenta of patients with preeclampsia remains poorly understood. The objective of this study was to identify correlations between LXRα, endoglin and preeclampsia and provide new...

Gestational diabetes and pregnancy-induced hypertension are common, and their relation is not well understood. The authors conducted a population-based case-control study using 1992-1998 Washington State birth certificate and hospital discharge records to investigate this relation. Consecutive cases of pregnancy-induced hypertension were divided into four groups based on International Classific...

In modern medicine, close attention is paid to the issues of reducing maternal morbidity and mortality, structure which hypertensive disorders gestation, especially preeclampsia, make a significant contribution. The complex pathomorphological mechanisms underlying etiopathogenesis this pregnancy complication occur long before manifestation pronounced clinical signs, complicates early diagnosis ...

maternal, fetal and neonatal complications are correlated with hypertensive disorders during pregnancy.  in this context, the maternal blood uric acid level is reported to be one of the prognostic factors in determining the prenatal outcome.  based on the existing data, the present descriptive study was performed on two groups of women with severe preeclampsia; the first group (n=53) with a uri...