INTRODUCTION Opitz trigonocephaly C syndrome (OTCS) is a rare malformation syndrome with the following features: synostosis of metopic suture, craniofacial abnormalities, severe mental retardation and a multitude of pathological findings affecting almost every organ system. OTCS is associated with a high mortality rate. CASE PRESENTATION We describe the case of a Caucasian male baby who died ...

Skull deformity in infants continues to be a diagnostic and therapeutic challenge. Deformational plagiocephaly is a common and somewhat benign cause of skull deformity in infants that must be distinguished from the more serious craniosynostosis, which occurs alone or as a syndrome. Examining an infant's head from above can help the physician distinguish true lambdoid synostosis from deformation...

STUDY DESIGN Retrospective case series. PURPOSE To assess the effect of non-kyphotic aligned congenital C3-4 synostosis on the adjacent segment in 10 patients. OVERVIEW OF LITERATURE In the cervical spine, fusion disease at the adjacent motion segments may be a risk factor for potential neurological compromise and death. METHODS Radiograms of 10 patients 13 to 69 years of age presenting w...

While the XYY and XXYY syndromes have been several time described in patients, the combination of both syndromes in an individual is a rare event and may result in a severe phenotype. In the present observation, a boy with congenital scoliosis due to segmented thoracic hemivertebra associated with radioulnar synostosis and congenital heart disease is described. Chromosome G-banding and FISH ana...

Acceptedteaching concerning the time and nature of synostosis of the manubrio-sternal joint is, generally speaking, erroneous. In agreeing with Fallopius and Eustachius, Coiter (1573) showed justifiable caution in stating that synostosis of this joint appears at the time at which the cranial sutures begin to be obliterated. This, of course, can mean any time after 30 years. Anatomists of the se...