background: the aim of the present study was to assess the mean corpuscular volume (mcv) as a surrogate marker for detecting early iron deficiency prior to definitive investigation and treatment. materials and methods: this study was done on one hundred students in swada preparatory school – sharkia governorate from 2010 to 2011. they were subdivided into three groups: group (a): comprised of 3...

PURPOSE Excessive brain iron accumulation contributes to cognitive impairments in hepatitis B virus (HBV)-related cirrhotic patients. The underlying mechanism remains unclear. Hepcidin, a liver-produced, 25-aminoacid peptide, is the major regulator of systemic iron metabolism. Abnormal hepcidin level is a key factor in some body iron accumulation or deficiency disorders, especially in those ass...

A simple, direct semi-micro method has been developed for serum iron and latent iron-binding capacity. For total serum iron, into a one cm cuvet are pipetted (a ) 1.5 ml of Na acetate buffer (pH 4.5) containing Na ascorbate and (b ) 0.3 ml of serum. The serum blank absorbance is measured at 562 nm, and 0.2 ml of ferrozine color reagent is added. After incubation (42°, 20 min), the absorbance is...

background: the aim of this study was to investigate the correlation between the cardiac and hepatic iron-overload as assessed by magnetic resonance imaging t2 star (mrit 2 -star) technique and serum ferritin level in patients with thalassemia major. methods: in this cross-sectional study we evaluated 170 patients in sayed shohada hospital in isfahan in the year of 2009, cardiac and hepatic iro...

background: among the many complications reported for cirrhosis, iron deficiency anemia (ida) has attracted much attention. this type of anemia, in contrast to other types of anemia, is easy to treat prophylactically, but if left untreated can lead to a poor quality of life. the aim of this study was to estimate the hemoglobin and serum iron levels among patients with liver cirrhosis for the ea...

Background: Alopecia Areate (AA) is a recurrent non-scarring patchy hair loss of autoimmune origin in a genetically susceptible individual although environmental factors may be contributory. The aim of this study is to evaluate serum iron and ferritin levels in patients with AA. Methods: Fifty patients of AA and 50 age and sex matched control subjects without any hair loss were studied. Results...

background: in the present study, blood serum level of metals were determined in malarial pa­tients and compared with those in the normal subjects without complication using atomic absorp­tion spectrometer. methods: for the determination of these metals twelve intravenous blood samples each from re­ferred malarial patients and a group of normal subjects were collected and immediately centri­fug...

Although serum iron determinations play an important role in the diagnostic process, the accuracy of routine methods is suspect. The poor performance of currently used methods is well documented in the quarterly College of American Pathologists survey reports. Compared with the 1990 method of the International Committee for Standardization in Haematology (ICSH), the 1978 ICSH Reference Method s...

The iron stores of 32 healthy pregnant women were evaluated longitudinally during pregnancy and 6 months post partum by serum ferritin assay and by bone marrow iron content. Half of the women were receiving oral iron while the others were not given iron supplementation. Women receiving iron could maintain their iron stores throughout the pregnancy. By contrast, women without iron therapy had lo...

abstract background: recent studies have suggested that oxidative stress (os) may have a contribution in the pathogenesis of endometriosis. however, the results of previous studies regarding os in endometriosis are controversial. the objective of this study was to compare the serum levels of os markers in endometriosis versus the control group. methods: this case-control study was carried out o...