نتایج جستجو برای: serous prognosis
تعداد نتایج: 125543 فیلتر نتایج به سال:
Endometrial biopsies are useful for evaluating endometrial disease, but the presence of non-endometrial, noncervical tissue is rare and is typically restricted to metastasis to the endometrial cavity. We report, for the first time, a case of an endometrial biopsy seeded with serous cells in a young patient with a known history of a serous borderline tumor of the ovary. Given the patient’s diagn...
The diagnosis of endometrial carcinoma requires histopathological confirmation. This diagnosis is made according to the WHO pathological classification. About 80% of endometrial carcinomas are of endometrioid type. Serous (5–10%), clear cell (1–5%), mucinous, mixed, squamous cell, transitional cell and undifferentiated carcinomas are other established subtypes. Endometrial carcinosarcoma is now...
•Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer.•Mutations in DNA polymerase ε gene (POLE) are detected in a subset of USC and confer a strong mutator phenotype.•USC patients diagnosed with POLE mutations experience a significantly better prognosis.
BACKGROUND The purpose of this retrospective study was to determine the prognosis of non-serous epithelial ovarian cancer (EOC) patients with exclusively retroperitoneal lymph node (LN) metastases, and to compare the prognosis of these women to that of patients who had abdominal peritoneal involvement. METHODS A multicenter, retrospective department database review was performed to identify p...
PURPOSE The study aim to identify novel molecular subtypes of ovarian cancer by gene expression profiling with linkage to clinical and pathologic features. EXPERIMENTAL DESIGN Microarray gene expression profiling was done on 285 serous and endometrioid tumors of the ovary, peritoneum, and fallopian tube. K-means clustering was applied to identify robust molecular subtypes. Statistical analysi...
Although high levels of tumor-infiltrating lymphocytes (TILs) generally correlate with good prognosis in high-grade serous ovarian cancer (HGSC) patients, little is known about the phenotype or specificity of these cells. We have recently demonstrated that TIL expressing the intra-epithelial lymphocyte marker CD103 (official name, integrin αE, ITGAE) abundantly infiltrate HGSCs, strongly correl...
PURPOSE Epithelial ovarian cancer has the highest mortality rate of all gynecological malignancies. We have shown that high RAN expression strongly correlates with high-grade and poor patient survival in epithelial ovarian cancer. However, as RAN is a small GTPase involved in two main biological functions, nucleo-cytoplasmic transport and mitosis, it is still unknown which of these functions as...
Primary mesotheliomas are rare tumours derived from the mesothelial cells of major serous cavities. They most commonly occur in the pleural cavity, but in recent years the incidence of peritoneal mesothelioma has been increasing. The prognosis for these tumours is generally poor, death normally occurring within one year of diagnosis, but can be improved by earlier diagnosis and aggressive manag...
BACKGROUND Epithelial ovarian cancer (EOC) is a spectrum of different diseases, which makes their treatment a challenge. Forkhead box M1 (FOXM1) is an oncogene aberrantly expressed in many solid cancers including serous EOC, but its role in non-serous EOCs remains undefined. We examined FOXM1 expression and its correlation to prognosis across the three major EOC subtypes, and its role in tumori...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید