spinal cord injury (sci) in humans remains a devastating and incurable disorder. a very important obstacle in axonal regeneration after spinal cord injury is astroglial scaring. the use of self-assembling peptide nanofiber, a hydrogel mimicking extracellular matrix, has been suggested as a scaffold for spinal cord regeneration and inhibition of astrogliosis. however, neurogenesis potential of l...

This study examined the association of novelty seeking, harm avoidance, and reward dependence with different types (suicide attempts vs. nonsuicidal self-injury) and aspects (medical risk, impulsiveness, suicide intent) of self-injury over a 12-month period. Fifty-five female patients with borderline personality disorder enrolled in clinical trials completed Cloninger's Temperament and Characte...

This research offers a description and analysis of the relatively hidden practice self-injury: cutting, burning, branding, bone breaking. Drawing on over 150 in-depth interviews tens thousands website postings, e-mail communications, Internet groups, we challenge psycho-medical depiction this phenomenon discuss ways that contemporary sociological self-injury has evolved to images population, et...

Deliberate self-injury is defined as the intentional, direct injuring of body tissue without suicidal intent. The present article reviews the empirical research on the functions of self-injury. This literature includes self-reports of reasons for self-injuring, descriptions of the phenomenology of self-injury, and laboratory studies examining the effects of self-injury proxies on affect and phy...

Non-suicidal self-injury (NSSI) refers to the intentional act of causing physical injury without a clear suicidal intent. Patients in dissociative state attempt fulfill an underlying psychological need by inflicting cutaneous wounds on themselves. The mechanisms NSSI can vary from mild severe depending degree soft tissue destruction. Self-destructive behavior triggered psychosis, different clas...

BACKGROUND Although early conceptualisations posited an inverse relationship between psychopathy and self-injury, little research has tested this. AIMS To examine the self-injurious thoughts and behaviours associated with psychopathy. METHODS Data from the MacArthur Violence Risk Assessment Project (N = 871) were used to examine homogenous subtypes of participants based on their responses t...

The role of pain in the practice of self-injury is not straightforward. Existing accounts suggest that self-injury does not cause 'physical' pain, however self-injury is also said to alleviate 'emotional' pain by inflicting 'physical' pain. This paper explores these tensions using sociological theories regarding the socio-cultural and subjective nature of pain. Analysis derives from in-depth, l...