background: investigation of tuberculosis (tb)-specific indices including prevalence of tb, mortality of tb cases excluding hiv, hiv/tb mortality, incidence of tb (all forms), hiv/tb incidence as well as case detection and related trends is a crucial step in evaluation of program performance and strategies success. besides, estimating the number and time of change points for tb incidence can he...

background: describing trend in tuberculosis (tb) over time can play an important role to assess the disease control strategies and predict the future morbidity and mortality. this study aimed to determine the incidence trend of smear‑positive pulmonary tuberculosis (sppt) in sub‑age and sex groups during the years of 1995–2012. methods: this retrospective cohort study was performed in 2015 by ...

background: leishmaniasis is a worldwide disease prevalent in tropical and sub- tropical countries in the world. characterization of inflammatory responses produced in cutaneous leishmaniasis has not yet been completed. methods: the specific primers were designed for ten pro-inflammatory genes including ccl4, ccl3, tnf-α, il-1α, il-12p35, il-12p40, ccl5, ccr5, il-1β and ifn- γ and their express...

The quantitative changes of the high mobility group (HMG) nonhistone chromosomal proteins in nondividing, differentiated peritoneal exudate neutrophils were identified by their solubility, electrophoretic mobility on both SDS and acetic acid gels, densitometric traces and elution profile on CM-sephadex. The results indicated that in neutrophils, HMGl undergoes a considerable reduction (80%...

background: during the initial phase of an infection, there is an upregulation of inducible nitric oxide synthase in the macrophages for the production of nitric oxide. this is followed by the recruitment of polymorphonuclear leukocytes (neutrophils) which release arginase. arginase competes with inducible nitric oxide synthase for a common substrate l-arginine. objective: to investigate whethe...

http://dx.doi.org/10.1016/j.jvcir.2015.08.009 1047-3203/ 2015 Elsevier Inc. All rights reserved. q This paper has been recommended for acceptance by M.T. Sun. ⇑ Corresponding author. Fax: +86 028 61830064. E-mail addresses: [email protected] (Q. Wu), [email protected] (H. Li), [email protected] (F. Meng), [email protected] (K.N. Ngan), eezsy @uestc.edu.cn (S. Zhu). Qingbo Wu a,⇑, Hongli...

protection of the mammary gland against mastitis-causing pathogens is mediated by many factors in thegland and blood circulation. the professional phagocytic cells of bovine udder, polymorphonuclearneutrophils (pmn) and macrophages, comprise the first line of defense against invading mastitis pathogens.most researchers now accept that the pmn is a key factor in the cows’ defense against intrama...

to evaluate the effect of intrauterine cephapirin on treatment of endometritis 39 holstein dairy cows that affected with postpartum endometritis were selected and randomly assigned to two experimental designs. in experiment 1, 6 out of 14 cows were 25 to 30 days after parturition were treated by intrauterine oxytetracycline. another 8 cows were treated by intrauterine cephapirin (metri-care). i...

background & objectives: neutrophils are the most important member of granulocytes & the first line of host defence against micro-organisms. they kill micro-organisms entering the body by phagocytic activity. one of the important phases of phagocytic activity is respiratory burst which can be effected by different drugs such as cimetidine. in this study the effects of cimetidine on respiratory ...