Apicomplexan parasites, including the human pathogens Toxoplasma gondii and Plasmodium falciparum, employ specialized secretory organelles (micronemes, rhoptries, dense granules) to invade and survive within host cells. Because molecules secreted from these organelles function at the host/parasite interface, their identification is important for understanding invasion mechanisms, and central to...

During their synthesis, a large fraction of proteins are directed to the secretory pathway. There are several models that aim to distinguish between different destinations along this pathway, however they rarely distinguish between known stages of this translocation process. This paper presents a translocation probability function which models the protein SRP-recruitment process – the first sta...

We describe a gland in the arthrodial membrane of coxa-trochanter articulation fourth pair legs Neotropical harvester Mischonyx squalidus Bertkau, 1880. Externally glandular area has rough appearance with pores on its surface, folds membrane. Internally, secretory cells have spherical vesicles, smooth endoplasmic reticulum, mitochondria and ducts that exit from cross Histochemical tests indicat...

The sweat eccrine and apocrine glands of human skin secrete many functionally significant substances, including hydrolytic enzymes, onto its surface through the mechanisms secretion, excretion recruitment. Shown is their recreational origin as a secretory product digestive glands—pepsinogen by stomach glands, α-amylase—by pancreas. Hydrolases in epidermal barrier provide hydrolysis proteins, ca...