Memory T cells expressing stem cell-like properties have been described recently. The capacity of self-renewal and differentiation into various memory/effector subsets make them attractive for adoptive T cell therapy to combat severe virus infections and tumors. The very few reports on human memory stem T cells (T(SCM)) are restricted to analyses on polyclonal T cells, but extensive data on Ag-...

The Sex comb on midleg (Scm) gene is a member of the Polycomb group (PcG) of genes in Drosophila melanogaster. The PcG genes encode transcriptional repressors required for proper spatial expression of homeotic genes. We report the isolation of new Scm mutations and the molecular characterization of the Scm gene. Scm mRNA is expressed maternally, at peak levels in early embryos and then at lower...

The objective of this study is to examine the compressive strength and durability of very high-volume SCM concrete. The prepared 36 concrete specimens were classified into two groups according to their designed 28-day compressive strength. For the high-volume SCM, the FA level was fixed at a weight ratio of 0.4 and the GGBS level varied between the weight ratio of 0.3 and 0.5, which resulted in...

Cellular pattern formation in the root epidermis of Arabidopsis occurs in a position-dependent manner, generating root-hair (H) cells contacting two underlying cortical cells and nonhair (N) cells contacting one cortical cell. SCRAMBLED (SCM), a leucine-rich repeat receptor-like kinase (LRR-RLK), mediates this process through its effect on a downstream transcription factor regulatory network. A...

In time-varying frequency selective channels, to obtain high-rate joint time-frequency diversity, linear dispersion coded orthogonal frequency division multiplexing (LDC-OFDM), has recently been proposed. Compared with OFDM systems, single-carrier systems may retain the advantages of lower PAPR and lower sensitivity to carrier frequency offset (CFO) effects, which motivates this paper to invest...

Background Indonesia comprises 17,000 islands and 495 districts. Decentralization mandates district health services, but ensuring proper supply chain management (SCM) capacity at the district level is a challenge. The ministry of health developed and implemented SCM training modules and guidelines; however, weaknesses in the system remain, particularly related to human resources. The ministry i...

We show that the announcement of SCM applications have a positive impact on the market value of firms using event study methodology. When SCM applications are disaggregated according to whether they are standalone SCM applications, or part of an enterprise system (SCM-ES) implementation, we find that the latter carry a significant value enhancement, while the former do not present a significant...

A lightweight version of the Feature Oriented Domain Analysis (FODA) method is applied to the Software Configuration Management (SCM) domain. Following a brief introduction to SCM, the domain model discussed in detail, covering the contextual, representational and operational features of SCM systems. A high level reference architecture for the SCM domain is analyzed to identify reusable compone...

Supply Chain Management Information Systems (SCM IS) are increasingly critical for synchronizing information among the customers and suppliers of a supply chain. Wide variation and overlap in the functionality of different SCM IS makes analysis and comparison difficult. Traditional flat taxonomies using one or two dimensions of functionality have limited utility for software selection and analy...

In recent years, there has been an increasing interest in using information technology to improve supply chain management (SCM) performance. This study examines the shareholder wealth effects of SCM software initiatives, and thereby contributes to the literature on IT investments and SCM. Specifically, we examined the abnormal stock returns to SCM software initiatives announced by firms between...