To determine the genetic basis of the resistance of Schistosoma mansoni to praziquantel (PZQ) and to understand whether the resistance is dominant or recessive trait, a schistosome cross was undertaken between a PZQ-susceptible and a PZQ-resistant isolate using infections of the single-sex cercariae which were identified by a direct W1-specific PCR technique. The resistances of F1 and F2 genera...

BACKGROUND A PCR-enzyme-linked immunosorbent assay (PCR-ELISA) was developed to overcome the need for sensitive techniques for the efficient diagnosis of Schistosoma infection in endemic settings with low parasitic burden. METHODOLOGY/PRINCIPAL FINDINGS This system amplifies a 121-base pair tandem repeat DNA sequence, immobilizes the resultant 5' biotinylated product on streptavidin-coated st...

In the present review, we will discuss the Schistosoma mansoni form, which is the most widely distributed schistosome in humans and is found both in the Old and New Worlds. The main features of the natural history of mansonic schistosomiasis are reviewed, with emphasis on the clinical forms of the disease, their diagnosis and treatment.

Schistosomiasis mekongi is prevalent in the Khong district of Lao PDR, made up of one big island, Khong, and numerous small islands in the Mekong River. Schistosoma mekongi is spread by Neotricula aperta as the intermediate host along the Mekong River. Therefore, even if an epidemic of S. mekongi were stamped out in a certain village, infection may recur if the source of infection is a village ...

Scanning electron microscopical (SEM) studies on the tegument of the bovid schistosomes, Schistosoma margrebowiei and Schistosoma mattheei have yielded conflicting results; certain authors observed the tubercles on the tegument of these species to be spined, while others reported that they are spineless. The present study indicates that the protrusion of tubercular spines is subject to phenotyp...

Schistosoma mansoni cercariae were removed from clear and turbid water by flocculation with Sudanese bentonite clays, with Moringa oleifera seeds as well as with pure bentonite. The flocculation technique employed corresponds to that used to clarify Nile water in Sudanese villages. Moringa seeds, pure bentonite and one type of bentonite clay were able to reduce the number of cercariae by more t...

In May, 2007 a total of 54 cattle and 47 buffaloes were examined for Schistosoma nasale infection at a municipality slaughterhouse in Kalpetta, Wayanad, India. Eleven point one percent of cattle and 23.4% of buffaloes were positive, all with only mild parasite loads, with fewer than 5 per animal. The prevalence of Schistosoma nasale among large ruminants in Wayanad, India is relatively low comp...

The behavior of the Schistosoma mansoni infection in patients with AIDS has not been explored. The case of a young woman with schistosomiasis mansoni, AIDS, and cytomegalovirus disease is reported. The authors suggest that the helminth was not a bystander in this case, or rather, by interfering with the host’s immune response, it set the stage for the development and/or aggravation of the viral...

A quartz-crystal microbalance immunosensor (QCM) has been developed for the direct determination of Schistosoma-japonicum-infected rabbit serum. A self-assembled monolayer with carboxyl groups was first coated on a gold electrode of a quartz-crystal resonator by the spontaneous adsorption of 3-mercaptopropionic acid. Schistosoma-japonicum molecular antigen of 32 kD molecular weight was then cov...

Schistosomiasis is the second most devastating tropical parasitic disease worldwide and responsible for many urological complications. However, glomerular injury a rare complication mainly described with Schistosoma haematobium. We describe first case of Schistosomia infection, associated to segmental focal hyalinosis in young Senegalese patient nephrotic syndrome responding perfectly well anti...