It is recognized that scatter correction can supply more accurate absolute quantification, and that iterative reconstruction results in better noise properties and significantly reduces streak artefacts; however, it is not entirely clear whether they produce significant changes in [18F]-FDG distribution of reconstructed 3D brain PET images relative to not scatter corrected images and analytic r...

UNLABELLED (201)Tl-Chloride ((201)Tl) is a myocardial perfusion SPECT agent with excellent biochemical properties commonly used for assessing tissue viability. However, cardiac (201)Tl SPECT images are severely degraded by photons scattered in the thorax. Accurate correction for this scatter is complicated by the nonuniform density and varied sizes of thoraxes, by the additional attenuation and...

BACKGROUND The aim of the study is to assess accuracy of activity quantification of 177Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamphlets 23 and 26. The performances of two scatter correction and three segmentation methods were compared. Additionally, the accuracy of tomographic and planar methods for determination of ...

-Our Monte Carlo PET simulation for a 3D PET scan is able to simulate ~5 million coincidence events per minute per minute on 300MHz Sun dual processor workstation. This is over two orders of magnitude faster than most other available Monte Carlo simulations for 3D PET and is fast enough to be employed as a scatter correction for 3D PET imaging. We have improved the accuracy of our simulation of...

We are developing an accelerated Monte Carlo simulation of PET that can be uscd for scatter correction of 3D PET datn. Our Monte Carlo technique accurately accounts for single, multiple, and dual Compton scatter events, attenuation through the patient bed, activity from outside the field of view, and the true energy response of the scanner. We have incorporated innovative sampling techniques th...

introduction: scatter radiation is one of the major sources of error in nuclear medicine data processing. different methods of scatter correction have been introduced in order to improve the quality of data. however the best method is to avoid recording of scatter photons in acquisition. the only difference between scattered and non-scattered photons is the energy. pulse height analyzer is the ...

Fully three-dimensional (3D) positron emission tomography (PET) can achieve high sensitivity of coincidence events, but the absence of inter-slice septa inevitably leads to increased scattered events. The scattered events can represent as much as 50% of the total detected events. In this research, we proposed a scatter correction method for 3D PET based on beam stoppers and dual-energy window a...

Received 12/27/2000; revised 2/26/2001; accepted 3/14/2001. For correspondence or reprints contact: Habib Zaidi, Ph.D., Division of Nuclear Medicine, Geneva University Hospital, CH-1211 Geneva, Switzerland. Tel: 41 22 372 72 58, Fax: 41 22 372 71 69, E-mail: [email protected] A new method to assess the scatter component in positron emission tomography (PET) based on estimating the low-freque...

PURPOSE Patient-specific dosimetry of lutetium-177 ((177)Lu)-DOTATATE treatment in neuroendocrine tumours is important, because uptake differs across patients. Single photon emission computer tomography (SPECT)-based dosimetry requires a conversion factor between the obtained counts and the activity, which depends on the collimator type, the utilized energy windows and the applied scatter corre...

UNLABELLED Quantitative PET with (15)O provides absolute values for cerebral blood flow (CBF), cerebral blood volume (CBV), cerebral metabolic rate of oxygen (CMRO(2)), and oxygen extraction fraction (OEF), which are used for assessment of brain pathophysiology. Absolute quantification relies on physically accurate measurement, which, thus far, has been achieved by 2-dimensional PET (2D PET), t...