Tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. It has broad spectrum activity, including Staphylococcus aureus infections. This is the first study that evaluated the activity of Tigecycline against Staphylococcus aureus isolated from biological samples in Iran. In vitro activity of tigecycline against 160 Staphylococcus aureus including 99 methicil...

OBJECTIVES To determine the relevance of nasal carriage of Staphylococcus aureus, either methicillin-sensitive (MSSA) or methicillin-resistant (MRSA), as a risk factor for the development of nosocomial S aureus bacteremia during an MRSA outbreak. PATIENTS AND METHODS In this prospective cohort study, 488 patients admitted to an intensive care unit (ICU) during a 1-year period were screened wi...

A biofilm is an aggregate of microorganisms in which cells adhere to biological or non-biological surfaces and is responsible for various infectious diseases. Infections caused by Staphylococcus aureus, including pneumonia, endocarditis, and osteomyelitis, are often associated with colonization and biofilm formation. Although lipoteichoic acid (LTA) is involved in biofilm formation, the specifi...

INTRODUCTION Staphylococcus aureus is a common cause of bacterial arthritis, which is associated with progressive bone loss in affected joints. We recently showed that S. aureus infection also induces a significant systemic bone loss in mice. This study was performed to assess the effect of estradiol treatment on the clinical course and outcome of S. aureus arthritis and on infection-induced bo...

introduction: thyroid gland is well known to resist infections by rich blood supply and lymphatic drainage,   high glandular content of iodine which can be bactericidal and separation of the gland from other structures of neck. primary thyroid abscess resulting from acute suppurative thyroiditis (ast) is an unusual type of head and neck infection and it is a rare condotion in children so that p...

background staphylococcus aureus is a major nosocomial pathogen world wide. mupirocin plays a crucial role in strategies designed to control outbreaks of s. aureus. objectives the aim of this study was to determine the frequency of mupirocin resistance in s. aureus strains isolated from nasal carriers among the hospitalized patients at kermanshah hospital, iran. patients and methods a total of ...

background: methicillin-resistant staphylococcus aureus (mrsa) is resistant to most antibiotics and is an important pathogen of nosocomial infections. the prevalence of community (ca-mrsa) and hospital acquired methicillin-resistant s. aureus (ha-mrsa) infection is increased. in this study we investigated the frequency of mrsa colonization and its antibiotic susceptibility in students of rafsan...

Staphylococcus aureus is the most common pathogen isolated from respiratory tract samples in cystic fibrosis (CF) cases. Rate of infection with S. aureus small-colony variants (SCVs) also is increasing in CF patients. In this study, we aimed to determine the prevalence, antibiotic susceptibility and genotypic property of S. aureus SCVs in respiratory tract samples of CF patients admitted to Ist...

During an outbreak of infections caused by methicillin-resistant (MR) Staphylococcus aureus in our burn unit, we conducted an extensive 10-week study to define the environmental epidemiology of the organism. The inanimate environment in patient rooms and adjacent areas was examined by using volumetric air samplers and Rodac plates. Airborne and surface level contamination with MR S. aureus was ...

conclusions carriage of pvl-positive s. aureus is common in this region, even in the low frequency of mrsa colonization. the detection of acme-arca gene in s. aureus isolates is a public-health concern and demands continued surveillance and close monitoring. results among the 813 subjects screened, 83 (10.2%) were persistent carriers, 86 (10.6%) were transient carriers and 644 (79.2%) cases wer...