There is significant regional variation in the etiologic agents responsible for hepatocellular carcinoma (HCC), which influences the genetic and epigenetic mechanisms of malignant transformation. The aim of the present study was to investigate the prevalence of allelic imbalance (AI) and CpG island methylation in HCCs from Australia and South Africa. Genomic DNA was extracted from malignant and...

This study was designed to determine the response of diverse mint genotypes to three commonly used cryopreservation techniques. Four mints [Mentha x piperita nothosubsp. citrata (Ehrh.) Briq.; M. canadensis L.; M. australis R. Br, and M. cunninghamii Benth] were cryopreserved using three protocols: controlled rate cooling (CC), encapsulation dehydration (ED) and PVS2 vitrification (VIT). Regrow...

The concern of this paper is the study of automated deduction methods for propositional modal logics. We use tableau proof-systems to show that Fitting's translation of the transitive modal logic S4 into T can be constructed in deterministic polynomial time. This result is exploited in order to establish a polynomial bound to the length of branches in both tableau and sequent proof search for t...

Abstract Chemical compositional data sets of archaeological artefacts are often analysed using standard statistical procedures. Adopting a different approach, we examine the major element oxides found in Parthian and Sasanian glazed pottery by identifying statistically important ratios conjunction with expert knowledge scientist during, rather than after, identification process. This results me...

Mints/X11s are neuronal adaptor proteins that bind to amyloidprecursor protein (APP). Previous studies suggested that Mint/X11 proteins influence APP cleavage and affect production of pathogenic amyloid(A ) peptides in Alzheimer’s disease; however, the biological significance of Mint/X11 binding to APP and their possible role in A production remain unclear. Here, we crossed conditional and cons...