TO THE EDITORS: Safier et al conclude that preexposure prophylaxis (PrEP) with oral emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) dosed the day before, day of, and day after intrauterine insemination effectively achieves pregnancy in serodifferent (human immunodeficiency virus [HIV]þ/HIVe) couples while avoiding HIV transmission. In this Journal in 2015, Mabileau et al proposed simi...

BACKGROUND Within the health system, limited attention is given to supporting the fertility and parenting desires on HIV-positive people. In this study, we explore health care providers' knowledge and perspectives on safer conception and alternate parenting strategies for HIV-positive people. METHODS Between November 2007 and January 2008, in-depth interviews were conducted with 28 health car...

Safer conception strategies to reduce the HIV transmission risk include antiretroviral therapy for HIV-positive partners, pre-exposure prophylaxis for HIV-negative partners, condomless sex limited to fertile periods, and home-based self-insemination. Resistance to taking treatment or cultural concerns may limit uptake of strategies and intervention success. Understanding the acceptability and p...

Care for women with HIV infection has specific challenges before conception and during pregnancy that should be addressed in a comprehensive, standardized plan of care. Preconception care for HIV-infected women includes health recommendations and counseling for safer sexual practices, contraception, and pregnancy planning. The goals are: (1) to improve the health of the woman before conception;...