Tay-Sachs disease is an autosomal recessive disorder of sphingolipid metabolism, caused by enzyme hexosaminidase A deficiency that leads to an accumulation of GM2 in neurocytes which results in progressive loss of neurological function. The accumulation of lipid in retinal ganglion cells that leads to a chalk-white appearance of the fundus called 'cherry red spot' is the hallmark of Tay-Sachs d...

The authors regret a flaw in the proof of a result in our paper [1] cited in the title. They would like to apologize for any inconvenience caused. This corrigendum provides corrected statements and proofs of such a result. (For theoretical background on the subject, see, for instance, Cvetković, Doob, and Sachs [5], Biggs [2], Brouwer, Cohen, and Neumaier [3], Brouwer and Haemers [4], Van Dam, ...

background: tay-sachs disease (tsd), or gm2 gangliosidosis, is a lethal autosomal recessive neurodegenerative disorder, which is caused by a deficiency of beta-hexosaminidase a (hexa), resulting in lysosomal accumulation of gm2 ganglioside. the aim of this study was to identify the tsd-causing mutations in an iranian population. methods: in this study, we examined 31 patients for tsd-causing mu...

Let (G) and min (G) be the largest and smallest eigenvalues of the adjacency matrix of a graph G. Our main results are: (i) If H is a proper subgraph of a connected graph G of order n and diameter D; then (G) (H) > 1 2D (G)n : (ii) If G is a connected nonbipartite graph of order n and diameter D, then (G) + min (G) > 2 2D (G)n : These bounds have the correct order of magnitude for large and D. ...

Suicide and aging: special issue of Aging & Mental Health Natalie Sachs-Ericsson, Kimberly Van Orden & Steven Zarit To cite this article: Natalie Sachs-Ericsson, Kimberly Van Orden & Steven Zarit (2016) Suicide and aging: special issue of Aging & Mental Health, Aging & Mental Health, 20:2, 110-112, DOI: 10.1080/13607863.2015.1099037 To link to this article: http://dx.doi.org/10.1080/13607863.20...

The relationship between the number of shoulder dislocations and the depth and percent of head involvement of the Hill-Sachs lesions was investigated in this study. Thirty patients with recurrent anterior dislocation of the shoulder were divided into three groups according to the numbers of dislocations they had presented: Group 1: 1 to 5 dislocations ; Group 2: 6 to 20; Group 3: over 20. The m...

For anterior instability with glenoid bone loss comprising 25% or more of the inferior glenoid diameter (inverted-pear glenoid), the consensus of recent authors is that glenoid bone grafting should be performed. Although the engaging Hill-Sachs lesion has been recognized as a risk factor for recurrent anterior instability, there has been no generally accepted method for quantifying the Hill-Sac...