We present in this paper the essential aspects of the S2 system. This is the internet realization of SEMPER: An active, multi-domain, space-based, object oriented design environment for integrated building performance modeling. We begin with an overview of SEMPER principles. We then present the component based system architecture of S2, which makes use of the Common Object Request Broker Archit...

Given any -tuple ( s1, s2, . . . , s ) of positive integers, there is an integer N = N ( s1, s2, . . . , s ) such that an orthogonal design of order 2 ( s1 + s2 + · · ·+ s ) and type ( 2s1, 2 s2, . . . , 2 s ) exists, for each n ≥ N . This complements a result of Eades et al. which in turn implies that if the positive integers s1, s2, . . . , s are all highly divisible by 2, then there is a ful...

The starfish SALMFamide neuropeptides S1 (GFNSALMFamide) and S2 (SGPYSFNSGLTFamide) are the prototypical members of a family of neuropeptides that act as muscle relaxants in echinoderms. Comparison of the bioactivity of S1 and S2 as muscle relaxants has revealed that S2 is ten times more potent than S1. Here we investigated a structural basis for this difference in potency by comparing the bioa...

We construct a topological charge of gauge field configurations on a fuzzy S2×S2 by using a Dirac operator satisfying the Ginsparg-Wilson relation. The topological charge defined on the fuzzy S2×S2 can be interpreted as a noncommutative (or matrix) generalization of the 2nd Chern character on S2 × S2. We further calculate the number of chiral zero modes of the Dirac operator in topologically no...