Somatosensation plays pivotal roles in the everyday motor control of humans. During active movement, there exists a prominent high-gamma (HG >50 Hz) power increase in the primary somatosensory cortex (S1), and this provides an important feature in relation to the decoding of movement in a brain-machine interface (BMI). However, one concern of BMI researchers is the inflation of the decoding per...

We present femtosecond time-resolved photoelectron spectra of adenine in a molecular beam, recorded at pump wavelengths of 250, 267, and 277 nm. This leads to initial excitation of the bright S2(pipi*). Close to the band origin (277 nm), the lifetime is several picoseconds. Higher vibronic levels (267 and 250 nm excitation) show much shorter lifetimes of t < 50 fs, and we observe strong couplin...

This study focused on the covariation of response speed and event-related potentials during response preparation and on whether these variations can be brought under experimental control. Two S1-S2 choice response tasks with temporal uncertainty were conducted. In Experiment 1, S1 was 100% informative. Fast subjects showed larger P3s with S1 than slow subjects. The terminal CNV (tCNV) increased...

A field study was conducted at three sites (S1-S3) of 500m longitudinal transect along the drain, where soil was irrigated by toxic metal rich brass and electroplating industrial effluent in suburban area of Moradabad, India. Spatial and seasonal variations of total heavy metal content in soil and their effect on physico-chemical and biological properties were studied in soil samples taken from...

We present on the fly surface hopping simulations of the dynamics of photoexcited acetone in the n → π* band, taking into account both the spin-orbit and the dynamic couplings and allowing for the C-C bond dissociation. The S0, S1, T1 and T2 states were considered and the propagation time was 50 ps. According to the simulation results, after excitation to S1 both Internal Conversion (IC) to S0 ...

Curcumin is a natural active product that has various pharmacological activities such as anti-inflammatory effects. Here, we report the synthesis and evaluation of 34 monocarbonyl curcumin analogs as novel anti-inflammatory agents. Among the analogs, the symmetrical heterocyclic type displayed the strongest inhibition of lipopolysaccharide (LPS)-stimulated expression of pro-inflammatory cytokin...

Supplementary Materials: The following are available online at http://www.mdpi.com/1999-4915/7/11/2919, Figure S1: DLS analysis of PV 3CD protein, Figure S2: PCA analysis reveal major motions of 3CD, Figure S3: MD simulations reveal multiple interfaces in WT and mutant 3CD, Figure S4: Mutations of 3CD in the crystal structure, Figure S5: Analysis of the 50 ns MD simulations of mutant PV 3CD, an...

The title azaazulene 3 was synthesized either by reaction of tropone with N-{(2-pyridyl)acetyl}pyridinium iodide in the presence of ammonium acetate or by palladium-catalyzed cross-couplings between 2-halo-1-azaazulene and 2-substituted pyridine. The compound shows relatively stronger basicity compared with 2,2’-bipyridyl. While 3 showed no emission from the S1 state but from the S2 state like ...